2004年度诺贝尔医学奖及科研伦理学

2004 Nobel Prize for Physiology or Medicine and Ethics in Science

一向从事免疫学研究的巴克1985年受到一篇关于嗅觉研究论文的吸引,开始从分子生物学角色研究气味分子和嗅觉的组织系统。她在1988—1991年期间屡经失败,终于以创新性思维获得了突破。1991年她和她的实验室主任阿克塞尔在世界著名的《细胞》杂志上发表了该领域中的奠基性论文。诺贝尔医学奖评委会将2004年度的该奖授予了他们,却在实际上和文字上都把阿氏放在前,而把巴氏放在后,从而成为科研伦理学中一大悖论。

As a researcher in immunology, Linda Buck was attracted by an article on sense of olfaction in 1985 and then began to investigate odor particles and the organization of sense of smell from the viewpoint of molecular biology from 1988. During the period of 1988 - 1991 she suffered many defeats in the research, but fortunately she made a breakthrough with her creative mind at last. Then she published a fundamental paper in the world- famous journal ＂ Cell＂ after the co - signature of Richard Axel, director of her laboratory. They were awarded 2004 Nobel Prize in Physiology or Medicine by The Assembly at Karolinska Institute. But it was really weird that she always occupied the second position after Axel both in practice and in written papers. This situation becomes a noticeable paradox in ethics of science.