急性肾盂肾炎临床特点与实验室指标的相关性分析

The Analysis of Correlation between Clinical Traits and Some Laboratory Indexes of Acute Pyelonephritis Patients

目的:分析急性肾盂肾炎(Acute Pyelonephritis,AP)反映病情的指标峰值体温(Tmax)、SIRS(全身炎症反应综合征)评分和热程(Febric Duration,FD)之间,及其与常用实验室指标血白细胞计数(WBC)、中性粒细胞百分率(N%)、C-反应蛋白(CRP)之间的相关性,并探讨其临床意义。方法:选择2005年12月至2006年4月我科新入院的非轻症AP患者24例,测定患者开始治疗前血常规、血清CRP值;记录Tmax和FD;探讨上述指标之间的相关性和临床意义。结果:AP患者Tmax、N%、血清CRP、SIRS评分和WBC与FD呈正相关(相关系数r分别为0.67、0.63、0.62、0.58和0.43),但其中仅Tmax、N%、血清CRP等指标在不同热程组别中有差异有显著性。结论:通过观察AP患者Tmax、基线血清CRP水平有助于判断FD;CRP较体温、血WBC计数能更敏感的反映机体的炎症状态。

Objective To investigate the correlation between the peak body temperature （Tmax） ,SIRS score and Febric Duration （FD） ,indexes that reflect illness state of Acute Pyelonephritis patients; and their correlation with commonly used laboratory parameters of white blood cell count （WBC）, neutrophil percentage （N%） and C-reactive protein （CRP）, and discuss their clinical significance. Methods Between December 2005 and April 2006,24 newly admitted non-mild AP patients were selected. Their baseline blood routine and CRP were determined, Tmax and FD recorded. The dependability and significance of those indexes were analyzed and discussed. Results The Tmax, N%, serum CRP level and SIRS score had positive correlation with FD（ Pearson coefficient r respectively equaled to 0. 67,0.63,0.62,0. 58 and O. 43）. But only Tmax, N% and CRP were significantly different between FD sub-groups. Conclusions It is helpful to predict FD through observing Tmax and baseline CRP among AP patients. CRP is more sensitive than WBC count and body temperature in reflecting body inflammation status.