期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

不同方法测量膈肌运动对胸腹部肿瘤放射治疗靶区位移影响的误差比较 被引量：3

下载PDF
导出
摘要 目的比较并分析X线模拟机、B超、计算机断层扫描仪(computer tomography,CT)、磁共振成像(magnetic resonance imaging,MRI)四种方法测量自由呼吸状态下膈肌的运动范围,旨在精确确定胸腹部肿瘤适形放射治疗计划靶区(planning tumor volume,PTV)范围。方法选取10名正常健康受试者,男∶女=1∶1,平均年龄51岁,先后以X线模拟定位机,CT,MRI,B超四种测量方法测量膈肌长径方向运动范围。X线模拟机和B超采用直视下测量并记录数据,CT,MRI采用Photoshop5.0软件叠加图像并计算膈肌运动范围。对4组数据进行分析处理。结果X线模拟机、B超、CT、MRI测量的四组数据中,X线模拟机测量膈肌运动平均值最大(15.4mm),CT测量的平均值最小(8.0mm),B超和MRI之间平均值相似(11.7mm和11.6mm),B超和MRI测量膈肌运动度差异无显著性(P>0.05),X线模拟机(或CT)测量膈肌运动范围与其他三者差异均有显著性(P<0.05)。结论对胸腹部肿瘤放疗患者,个体化考虑呼吸运动影响决定PTV范围和治疗计划是非常必要的。B超经济实用,简单快捷,又是临床工作中最常用的影像学工具之一,可以作为临床检查呼吸运动范围常规。
作者 官键 刘来昱 陈龙华 李启生 刘英 王宏梅
机构地区 南方医科大学南方医院放疗科 南方医科大学南方医院呼吸内科
出处 《广东医学》 CAS CSCD 北大核心 2007年第6期910-912,共3页 Guangdong Medical Journal
基金 广东省自然科学基金重点项目(编号:013056)
关键词 呼吸运动 靶区位移 放射治疗
分类号 R445.2 [医药卫生—影像医学与核医学]
  • 相关文献

参考文献16

  • 1HANLY J,DEEBIOS M M,RABEN G S,et al.Deep inspiration breathing-hold technique for lung tumors:The potential value of targer immobilization and reduced lung density in dose escalation[J].Int J Radiat Oncol Biol Phys,1996,36(Suppl):188.
  • 2李宝生,於文雪,尹勇,李松毅,于金明.应用模拟定位机对肺癌肿块运动的研究[J].东南大学学报（自然科学版）,2002,32(4):590-593. 被引量：19
  • 3SHIMIZU S,SHIRTO H,AOYAMA H,et al.High-speed magnetic resonance imaging for four-dimensional treatment planning of conformal radiotherapy of moving body tumors[J].Int J Radiat Oncol Biol Phys,2000,48:471 -474.
  • 4TIMMERMAN R D,KAVANAGH B D,CHO L C,et al.Stereotactic body radiation therapy in multiple organ sites[J].J Clin Oncol,2007,25 (8):947-952.
  • 5LI T,XING L,MUNRO P,et al.Four-dimensional cone-beam computed tomography using an on-board imager[J].Med Phys,2006,33(10):3 825 -3 833.
  • 6LI X,ZHANG P,MAH D,et al.Novel lung IMRT planning algorithms with nonuniform dose delivery strategy to account for respiratory motion[J].Med Phys,2006,33(9):3 390 -3 398.
  • 7SHIMIZU S,SHIRATO H,KAGEI K,et al.impact of respiration movement on the computed tomographic images of small lung tumors in three-dimen-tional radiotherapy[J].Int J Radiat Oncol Biol Phys,2000,46(5):1 127 -1 133.
  • 8EKBERG L,HOLMBERG O,WITTGREN L,et al.What margins should be added to the clinical target volume in radiotherapy treatment planning for lung cancer?[J].Radiother Oncol,1998,48(1):71 -77.
  • 9ARGUE T,ITAMI J,ARGUE M,et al.Target volume definition for upper abdomen irradiation using CT scans obtained inhale and exhale phase[J].Int J Radiat Oncol Biol Phys,2000,48:465 -469.
  • 10DANVIS S C,HILL A L,HOLMES R B,et al.Ultrasound quantitation of respiratory organ motion in the upper abdomen[J].Br J Radiol,1994,67:1 096 -1 102.

二级参考文献15

  • 1[1]Ohara K, Okumura T, Akisada M, et al. Irradiation synchronized with respiration gate[J]. Int J Radiat Oncol Biol Phys,1989,17:853-857.
  • 2[2]Kubo H D, Hill B C. Respiration gated radiotherapy treatment: a technical study[J]. Phys Med Biol,1996,41:83-91.
  • 3[3]Rosenzweig K, Hanley J, Mah D, et al. The deep inspiration breath-hold technique in the treatment of inoperable non-small-cell lung cancer[J]. Int J Radiat Oncol Biol Phys,2000,48:81-87.
  • 4[4]Wong J W, Sharpe M B, Jaffray D A, et al. The use of active breathing control (ABC) to reduce margin for breathing motion[J]. Int J Radiat Oncol Biol Phys,1999,44:911-919.
  • 5[5]Shirato H, Shimizu S, Kitamura K, et al. Four-dimensional treatment planning and fluoroscopic real-time tumor tracking radiotherapy for moving tumor[J]. Int J Radiat Oncol Biol Phys,2000,48:435-442.
  • 6[6]Murphy M J, Cox R S. The accuracy of does localization for an image guided frameless radiosurgery[J]. Med Phys,1996,23:2043-2049.
  • 7[7]Rajapakshe R, Shalev S. Output stability of a linear accelerator during the first three seconds[J]. Med Phys,1996,23:517-519.
  • 8Ross C, Hussey DH, Edward C, et al. Analysis of movement of intrathoracic neoplasms using ultrafast computerized tomography. Int J Radiat Oncol Biol Phys, 1990, 18:671-677.
  • 9Balter JM, Ten-Haken RK, Lawrence TS, et al. Uncertainties in CTbased radiation therapy treatment planning associated with patient breathing. Int J Radiat Oncol Biol Phys, 1996, 36:167-174.
  • 10Ekberg L, Holmberg O, Wittgren L, et al. What margins should be added to the clinical target volume in radiotherapy treatment planning for lung cancer? Radiother Oncol, 1998,48:71-77.

共引文献38

同被引文献32

  • 1高宏,张昕,袁慧琴,梁军.体部伽玛刀整个治疗流程中的几点体会[J].医疗卫生装备,2005,26(8):60-60. 被引量：4
  • 2Shimizu S, Shirato H, Aoyama H, et al. High-speed magnetic resonance imaging for four-dimensional treatment planning of conformal radiotherapy moving body tumora[J].Int J Radiat Oncol Biol Phys, 2000,48(2) :471 -474.
  • 3Dason LA, Brock KK, Kazanjian S, et al. The reproducibility of organ position using active breahing control during liver radiotherapy[ J]. Int J Radiat Oncol Biol Phys,2001,51 (5) :1 410-1 421.
  • 4Baiter J, Brock K, Litzenberg D, et al. Daily largeting of intrahepatic tumors for radiotherapy [ J ]. Int J Radiat Oncol Biol Phys, 2003,55 (3) :266 -271.
  • 5Wagman R, Yorke E, Ford E, et al. Respiratory gating for liver tumors : using in dose escalation [ J ]. Int J Radiat Oncol Biol Phys, 2003,55(3) :659 -668.
  • 6Ruan D, Fessler JA, Baiter JM, et ai. Exploring breathing pattern irregularity with projection-based method [ J ]. Med Phys, 2006, 33 (7) :2 491 -2 499.
  • 7Blackall JM,Ahmad S,Mquel ME,et al. MRI-based measurements of respiratory motion variability and assessment of mag/ng strategies for radiotherapy planning[J]. Phys Med Biol,2006,51 (17):4 147-4 169.
  • 8Wu A, Linder G, Kalend A,et al. Physics of gamma knife approach on convergent beams in stereotactic radiosurgery[J]. Int J Radiat On- col Biol Phys, 1990,18 : 941-949.
  • 9Wu A. Physics and dosimetry of gamma knife[J]. Neurosurg Clin North Am, 1992,3:35-50.
  • 10Maitz A, Wu A. Treatment planning of sterotaetic convergent gamma- ray irradiation using Co sources[J]. Medical Dosimetry, 1998,23 (3) : 169-175.

引证文献3

二级引证文献4

广东医学
2007年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部