卡托普利治疗对海勤人员高血压患者生活质量的影响

Effects of captopril on quality of life of seaman patients with essential hypertension

目的:探讨卡托普利治疗对海勤人员高血压患者生活质量的影响。方法:对海勤人员Ⅰ、Ⅱ期高血压病77例进行卡托普利治疗前后生活质量变化的评定以及收缩压和舒张压变化的评定,与普奈洛尔组比较。结果:与治疗前比较海勤人员Ⅰ、Ⅱ期高血压病患者经卡托普利组治疗后血压下降了18.2/13.6 mmHg(P<0.01);自觉健康状况、情感积极性以及工作状况分值均明显增高(P<0.01);心理忧伤分值明显降低(P<0.01);性生活分值没有变化。普奈洛尔组治疗后血压下降了17.2/12.6 mmHg(P<0.01);其余分值没有变化。结论:卡托普利不仅能有效地降低海勤人员Ⅰ、Ⅱ期高血压病患者的血压水平,而且能提高其生活质量。

Objective： To observe the effects of eaptopril on quality of life （QOL） of seaman patients with essential hypertension. Methods：77 seaman patients with Ⅰ to Ⅱstage essential hypertension were treated with captopril and 54 ones were treated with propanolol for 8 weeks. Their QOL were evaluated by QOL questionnaire before and after the treatment. Results： After the treatment, the blood pressure decreased 18. 2/13. 6 mmHg in eaptopril group and 17. 2/12. 6 mmHg in propanolol group and the difference of the decreased blood pressure was not significant（P〉0. 05）. The perceived health, positive affect and work well - being scores were significantly higher and psychological distress scores were significantly lower after the treatment than those before the treatment in the captopril group. But the QOL scores after and before the treatment were similar in propanolol group（P〉0. 05）. Condusion：Captoprol is not only effective in lowering blood pressure, but also effective in improving QOL of seaman patients with essential hypertension.