PICU呼吸机相关肺炎36例临床特征与病原学分析

Clinic and Pathogenic Analysis of 36 Cases with Ventilator Associated Pneumonia (VAP) in PICU

目的分析小儿呼吸机相关肺炎(VAP)的临床和病原学特征。方法回顾我院PICU 4年来VAP患儿的临床和病原学特征。结果93例机械通气患儿有36例发生VAP,发生率为38.7%,死亡12例,共培养出致病的革兰氏阴性杆菌22株,革兰氏阳性菌9株,主要病原是铜绿假单胞菌。结论VAP感染的患儿临床预后相对较差,且VAP感染的细菌以革兰氏阴性杆菌为主。

Objective To analyze clinical and aetiological characteristics in children with ventilator associated pneumonia （VAP）. Methods To review the clinical data and test results of aetiology in children with VAP. Results Among 93 children treated with mechanical ventilation,36 children with VAP were diagnosed. The incidence of VAP was 38.7% ,22 Gram-negative bacteria was isolated, the predominant pathogen was paseudomonas aeruginosa in patients with VAP. Conclusion The majority of bacteria isdated in patients with VAP are Gram-negative, and the patients with VAP are more serious than those without VAP in PICU.