实验动物遗传工程——功能基因组时代的研究平台

Laboratory Animal Genetic Technologies :the Technological Platform in the Functional Genomics Era

本文就实验动物遗传工程在研究基因功能及其表达调控、阐明疾病发生机理、寻找药物治疗靶点等方面的技术突破做了综述.

In the functional genomics era, the researches of life sciences would be much more closely related to laboratory animal technologies. As the development and optimization progressed, laboratory animal genetic technologies provide a powerful tool for life science investigations. The authors reviewed the applications of these technologies in the fields of decoding gene function, gene expression regulation, pathology and validating drug targets , etc.