妊娠期糖尿病危险因素的研究进展

Advancement in research on risk factors of GDM

随着妊娠期糖尿病发病率的逐年上升,其危险因素的研究受到人们的广泛关注。炎症、抗氧化剂、瘦素、多囊卵巢综合征、高血红蛋白血症和高铁血症等对妊娠期糖尿病的发病可能有一定的影响。年龄、产次、孕期体重增长、巨大儿分娩史及其他不明原因的不良孕产史等,这些妊娠期糖尿病的经典危险因素已经得到人们的认可。研究妊娠期糖尿病的危险因素并早期干预,可降低高危人群糖尿病的发病率,有效预防母婴并发症的发生。

With increasing prevalence of gestational diabetes mellitus （GDM） year by year, the study on risk factors of GDM attracts more attention. Some risk factors such as inflammation, antioxidant, leptin, PCOS, hyperhemoglobinemia and hyperferremia maybe have some influences on development of GDM. Age, parity, weight increase during pregnancy, macrosomia delivery history and other unexplained adverse pregnancy and delivery histories all have been regarded classic risk factors of GDM. To study risk factors of GDM and then to give early intervention can reduce prevalence of GDM in the high risk population, and effectively prevent occurrence of complications of the maternity and the infant.