摘要
乙酰氧基胡椒酚乙酸酯(ACA)是一种从高良姜中提取的小分子天然化合物,具有抗肿瘤、杀菌、保护胃粘膜和抗艾滋病等生物学功能。大量的体内体外实验表明,ACA的抗肿瘤活性是广谱的,并且没有明显的副作用。ACA分子水平的可能作用方式在NF-κB信号途径的研究中得到了大致的确定。ACA在未来的临床和基础研究中将成为一种重要药物。
1 '-Acetoxychavicol acetate (ACA) is a kind of natural small molecular chemical compound, which is extracted from galangal. ACA possesses a lot of biological activities, such as anti-tumor, antibacterial, gastro-protective and anti-HIV activities. Many in vivo experiment results showed that ACA has no significant side effect in treatment. The mechanism research located ACA effect in the NF-kB signal pathway. ACA may play more and more important role in clinical and theoretical research in the future.
出处
《国外医学(药学分册)》
2007年第3期181-186,共6页
Foreign Medical Sciences(Section of Pharmarcy)