原发性中枢神经系统淋巴瘤的MRI

MRI characteristics of primary central nervous system lymphomas

目的:探讨免疫功能正常人原发性中枢神经系统淋巴瘤(PCNSL)的常规MRI表现。资料与方法:对21例经手术病理证实的PCNSL的MRI表现进行回顾分析,其中男14例,女7例,平均年龄49.6岁。结果:21例患者共检出30个病灶,其MRI表现具有如下特点:①病灶T1WI多呈低或等信号,T2WI呈等或稍高信号,单发或多发,境界清晰。②轻中度瘤周水肿,并可见“火焰样”特征性水肿。③增强后病灶多明显均匀强化;“缺口征”、“尖角征”的出现具有特异性。结论:传统MRI在PCNSL的诊断中起着重要的作用。

Objective： To analyse MRI findings of primary central nervous system lymphoma （PCNSL） in immunocompetent patients. Materials and Methods： MRI findings in 21 patients with pathologically proved PCNSL were analyzed retrospectively, 14 male and 7 female, mean age, 49.6 years old. Results： Thirty lesions were identified in 21 patients. The MRI findings of PCNSL were as follows： （1）hypo- or iso-intense on T1WI and iso- or slightly hyper-intense on T2WI, solitary or multiple well-defined lesions; （2）slight or moderate peritumoral edema, and characteristic flame-like edema; （3）enhancement is intense and homogeneous, the presence of ＂incision sign＂ and ＂angular sign＂ are more specific. Conclusion： Conventional MRI plays an important role in the diagnosis of PCNSL.