期刊文献+

2型糖尿病胰岛素抵抗影响因素的临床观察

下载PDF
导出
摘要 目的:探讨2型糖尿病C-反应蛋白(CRP)与胰岛素抵抗(IR)的关系。方法:检测112例2型糖尿病患者空腹血糖(FBG)、空腹胰岛素(FINS)、C-反应蛋白及高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、总胆固醇(TC)等指标,并测量血压、体质量、身高、腰围、臀围,计算体质量指数(BMI)、腰臀比(WHR)等,分析C-反应蛋白与胰岛素抵抗的关系。结果:2型糖尿病C-反应蛋白与胰岛素抵抗呈正相关。结论:对2型糖尿病除控制血糖外,降低CRP治疗应成为2型糖尿病综合治疗的重要部分。
出处 《中国医药导报》 CAS 2007年第06S期38-39,共2页 China Medical Herald
  • 相关文献

参考文献1

二级参考文献22

  • 1Pandolfi A, Gisccari A. Acute hyperglycemia and acute hyperinsulinemia decrease plasm flbrinolytic activity and increase plasminogen activator inhibitor type 1 in the rat [ J ] .Acta Diabetol,2001,38:71-76.
  • 2Yamagishi S, Edelstein D, Du X. et al. Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase [ J ]. J Biol Chem,2001,276:25096-25100.
  • 3Unger R H, Zhou Y T. Lipotoxicity of β-cell in obesity and in other causes of fatty acid spillover [ J]. Diabetes, 2001,50(Suppl 1) :S118-S121.
  • 4Barbora V, Christian W, Robert S, et al. High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes[J] . Diabetes, 2002,51 : 455-461.
  • 5Robort S, Lindsay J K, Robext L H, et al. Gamma globulin level predict type 2 diabetes in the Pima Indian population[ J] Diabetes, 2001,50 : 1598-1603.
  • 6Walder K,Lakshmi K,Janine S,et al.Tanis: a link between type 2 diabetes and inflammation? [J]. Diabetes,2002,51:1859-1866.
  • 7Pradhan A D, Manson J E, Nader R, et al. C-reactive protein, interleukin-6, and risk of developing type 2 diabetes mellitus[ J] .JAMA ,2001,286:327-334.
  • 8Hrnciar J,Garbor D, Hrnciarova M, et al. Relation between cytokine (TNF-alpha, IL-6 and 1) and homocysteine in android obesity and the phenomenon of insulin resistance syndromes[ J]. Vnilr Lek, 1999,45 : 11-16.
  • 9Esposito K, Nappo F, Marfella R, et al. Inflammation cytokine concentrations are acutely increased by hyperglycemia in human : role of oxidative stress[J ] . Circulation, 2002,106 : 2067-2072.
  • 10Philip A, Subramanian R, Chunling L, et al. Adipose tissue tumor necrosis factor and interleukin-6, expression in obesity and insulin resistance [ J ]. Am J Physiol Endocrinol Metab,2001,280.E745-E751.

共引文献43

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部