摘要
目的:研究露珠杜鹃(Rhododendron irroratum Franch)的化学成分。方法:采用硅胶柱色谱、Sephadex LH-20柱色谱,重结晶等手段进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果:从露珠杜鹃中分离并鉴定了11个化合物,分别为:β-谷甾醇(1),乙酸橙酰胺(2),β-胡萝卜亭(3),齐墩果酸(4),3,4-二羟基苯甲酸(5),2,3-二羟基苯甲酸(6),没食子酸(7),山柰酚-3-0-β—D-葡萄糖苷(8),山柰酚-3-O-β-D-半乳糖(9)槲皮苷(10),杨梅素-3-O-β-D-葡萄糖苷(11)。结论:化合物1~11为首次从该植物中分得,化合物2,5~7,9和11为首次从该属植物中分离得到。
Objective :To study the chemical constituents of Rhododendron irroratum Franch. Methods: Com- pounds were isolated by silica gel and Sephadex LH-20 column chromatography and the structures were elucida-ted on the basis of spectral characteristics. Results: Eleven compounds were isolated and identified from R. ir-roratum Franch. as 13-daucosterol (1),aurantiamid acetate (2),β-daucosterol(3),oleanolic acid (4),3,4-di-hydroxybenzoic acid (5),2,3-dihydroxybenzoic acid(6),gallic acid (7),kaempferol-3-O-β-D-glucoside(8),kaempferol-3-O-β-D-galactoside(9), quercitrin(10),myricetin-3-O-β-D-glucoside(11).Cnclusion: All the eleven compounds were obtained from this plant for the first time, and compounds 2,5~7,9 and 11 were isola-ted from Rhododendron for the first time.
出处
《药学与临床研究》
2007年第3期199-201,共3页
Pharmaceutical and Clinical Research
关键词
露珠杜鹃
化学成分
Rhododendron irroratum Franch.
Chemical constituents