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冠心病合并高血压患者脉压与冠状动脉病变程度及心功能的相关性研究 被引量:1

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摘要 目的探讨冠心病合并高血压患者的脉压与冠状动脉病变程度及心功能的相关性。方法选择经冠脉造影证实的冠心病且合并高血压患者248例,男161例,女87例,平均年龄65.7岁,急性心肌梗死合并有高血压122例,心绞痛合并高血压126例,作为二个大组,每组又分为两个亚组,分为低脉压组(PP<60mmHg)和高脉压组(PP≥60mmHg),每一组60例左右。在每一个大组内和大组之间,对冠状动脉病变程度(冠脉狭窄支数、狭窄程度)、血压参数(SBP、DBP、MBP、PP)、心功能参数(EF、E/A值)、舒张末期室间隔厚度(ⅣSD)、舒张末期后壁厚度(LVPWD)、左室重量指数(LVMI)进行比较。结果①PP≥60mmHg组病人冠状动脉3支血管病变的患病率显著增高(P<0.05)。②随着PP增大,左心室收缩及舒张功能均明显的降低,PP与患者左心功能不全发生存在明显的相关性。结论PP高的冠心病病人较PP低的冠心病病人冠状动脉病变较为严重,PP与有冠状动脉病变程度有相关性。PP是左心功能不全发生的一个重要的相关因素,且随着PP增大,左心室收缩及舒张功能均明显的降低。
出处 《济宁医学院学报》 2007年第2期112-114,共3页 Journal of Jining Medical University
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参考文献14

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