N-羟甲基-2,3-二丁硫基四硫富瓦烯并[6,7-c]吡咯的合成

Synthesis of N-hydroxymethyl-2,3-dibutylthiotetrathiafulvaleno[6,7-c] pyrrole

从4,5-二丁硫基-1,3-二硫杂环戊二烯-2-酮和N-对苯磺酰基-2-硫代-1,3-二硫杂环戊二烯并[4,5-c]吡咯出发,经交叉偶联、去保护得2,3-二丁硫基四硫富瓦烯并[6,7-c]吡咯(4)。化合物4在碱存在下与甲醛水溶液(37%)反应生成N-羟甲基化的产物。用核磁共振氢谱研究了标题化合物在不同极性溶剂中的偶合行为。

2, 3-Dibutylthiotetrathiafulvaleno [ 6, 7-c ] pyrrole （ 4 ） was obtained from 4,5-dibutylthio-1,3-dithiole-2-one and N-tosyl-2-thiono-1,3-dithiolo [ 4,5-c ] pyrrele by means of the cresscoupling and deprotection process. In the presence of an alkali,4 reacted with formalin （with a formaldehyde concentration of 37 % ） to give N-hydrexymethyl product（5 ）. The coupling behavior of 5 in different polar solvents was studied with ^1HNMR.