1Shao RG, Cao CX, Shimizu T, O'Connor PM, Kohn KW,Pommier Y. Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine in human cancer cell lines, possibly influenced by p53 function. Cancer Res 1997; 57: 4029-35.
2Bunch RT, Eastman A. Enhancement of cisplatin-induced cytotoxicity by 7-hydroxystaurosporine (UCN-01), a new G2 checkpoint inhibitor. Clin Cancer Res 1996; 2: 791-7.
3Bunch RT, Eastman A. 7-hydroxystaurosporine (UCN-01) causes redistribution of proliferating cell nuclear antigen and abrogates cisplatin-induced S phase arrest in Chinese hamster ovary cells. Cell Growth Differ 1997; 8: 779-88.
4Shao RG, Cao CX, Zhang H, Kohn KW, Wold MS, Pommier Y. Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA -dependent protein kinase and dissociates RPA: DNA-PK complexes. EMBO J1999; 18: 1397-406.
5Akinaga S, Gomi K, Morimoto M, Tomaoki T, Okabe M.Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models. Cancer Res 1991; 51: 4888-92.
6Seynaeve CM, Kazanietz MG, Blumberg PM, Sausville EA,Worland PJ. Differential inhibition of protein kinase C isozymes by, UCN-01, a staurosporine analogue. Mol Pharmacol 1994; 45: 1207-14.
7Akinaga S, Nomura K, Gomi K, Okabe M. Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01 a selective inhibitor of protein kinase C. Cancer Chemother Pharmacol 1993; 32: 183-9.
8Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, et al. Conservation of the Chkl checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 1997; 277: 1497- 501.
9Rodrigues NR, Rowan A, Smith MEE Kerr IB, Bodmer WF,Gannon JV, et al. p53 mutations in colorectal cancer. Proc Natl Acad Sci USA 1990; 87: 7555-9.
10Akiyama T, Yoshida T, Tsujita T, Shimizu M, Mizukami T,Okabe M. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cipl/WAF1/Sdi 1 in p53-mutated human epidermoid carcinoma A431 cells.Cancer Res 19976; 57: 1495-501.
9Herman Antosiewicz A, Stan S D, Hahm E K, et al.Activation of a novel ataxia-telangieetasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a p romising cancer ehemop reventive constituent of processed garlic[J]. Mol Cancer Ther, 2007, 6(4): 1249-1261.
10Zaehos G, Black E J, Walker M, et al. Chkl is required for sp indle checkpoint funetion[J]. Dev Cell, 2007, 12(2) :247-260.
