针刺治疗痰瘀阻络型高血压病临床观察

Clinical observation on acupuncture for treatment of hypertension of phlegm-stasis blocking collateral type

目的:探讨针刺治疗痰瘀阻络型高血压病的临床疗效及作用机理。方法:将60例高血压病患者随机分为治疗组(30例)和对照组(30例)。治疗组针刺风池、曲池、内关、足三里、丰隆、太冲,配合口服卡托普利治疗;对照组口服卡托普利,疗程4周。观察两组治疗前后血压、临床症状、血液流变学指标及C-反应蛋白(CRP)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)含量变化。结果:治疗组血压明显下降,CRP、TC、TG、LDL含量均降低,血液流变学指标改善及HDL升高,临床证候积分及单项症状疗效改善明显,与治疗前及对照组比较差异均有非常显著性意义(P<0.01)。结论:针刺降血压效果明显,同时逆转或延迟动脉粥样硬化的进程,其机理可能与保护血管内皮功能的作用有关。

To explore the clinical therapeutic effect of acupuncture on hypertension of phlegm-stasis blocking collateral type and the mechanism. Methods Sixty cases of hypertension were randomly divided into a treatment group and a control group, 30 cases in each group. The treatment group were treated with acupuncture at Fengchi （GB 20）, Quchi （LI 11）, Neiguan （PC 6）, Zusanli （ST 36）, Fenglong （ST 40）, Taichong （LR 3）, and oral administration of Captori, and the control group only with Captoril, for 4 therapeutic courses. The changes of blood pressure, clinical symptoms, hemorheologic parameters, C-reactive protein （CRP）, TC, TG, HDL and LDL levels after treatment were observed. Results In the treatment group, blood pressure significantly decreased, and contents of CRP, TC, TG and LDL decreased, the hemorheologic parameters improved and HDL level increased. Both the cumulative scores of clinical symptoms and the therapeutic effect for each symptom were improved significantly, with very significant differences as compared with those before treatment and the control group （P〈0.01）. Conclusion Acupuncture treatment has obvious effect of decreasing blood pressure, and reverses or delays the course of atherosclerosis, which mechanisms are possibly related with the function of protecting vascular endothelium.