蛋白质亚细胞定位的生物信息学研究

Bioinformatics Research in Subcellular Localization of Protein

细胞中蛋白质合成后被转运到特定的细胞器中,只有转运到正确的部位才能参与细胞的各种生命活动,如果定位发生偏差,将会对细胞功能甚至生命产生重大影响.蛋白质的亚细胞定位是蛋白质功能研究的重要方面,也是生物信息学中的热点问题,数据库的构建和亚细胞定位分析及预测加速了蛋白质结构和功能的研究.

Protein is transported to specific subcellular localization after it is synthesized in cells, which is crucial to its function. Inaccurate destination will have great impact on cellular function or even life. Protein subcellular localization, which is one of the important areas in protein function research, is the hot issue in bioinformatics. Databases, analyses and prediction of subcellular localization accelerate the research of protein structure and function.