期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

基因组表观重编程对体细胞核移植成功率的影响 被引量：2

Effect of Genome Epigenetic Reprogramming on the Efficiency of Somatic Nuclear Transfer Technique
下载PDF
导出
摘要 基因组表观重编程缺陷是影响体细胞核移植效率的主要因素,本文讨论了表观重编程的两大主要机制——DNA甲基化及组蛋白修饰及其对体细胞核移植重构胚胎发育的影响,并综述了几种促进核重编程的方法。 The deficiency in genome epigenetic reprogramming is the main factor caused the low efficiency of the somatic nuclear transfer technique. The major epigenetic reprogramming mechanisms-DNA methylation and the modification of histones and their effects on reconstructed embryos were discussed in the article, furthermore, several methods for complete epigenetic reprogramming were also summaried in the article.
作者 李俊 桑润滋
机构地区 河北农业大学动物科技学院
出处 《中国畜牧杂志》 CAS 北大核心 2007年第11期46-48,共3页 Chinese Journal of Animal Science
关键词 基因组表观重编程 体细胞核移植 综述 genome epigenetic reprogramming somatic nuclear transfer technique a review
分类号 Q784 [生物学—分子生物学]
  • 相关文献

参考文献15

  • 1Keefer C L,Keyston R,Lazaris A,et al.Production of cloned goats after nuclear transfer using adult somatic cells[J].Biol Reprod,2002,66:199-203.
  • 2Cibelli J B,Campbell K H,Seidel G E,et al.The health profile of cloned animals[J].Nat Bioteehnol,2002,20:13-14.
  • 3Young L E,SinClair K D,Wilmut I.Large offspring syndrome in cattle and sheep[J].Rev Reprod,1998,3:155.
  • 4Danials R,Hall V,Trounson A O.Analysis of gene transcription in bovine nuclear transfer embryos reconstructed with granulose cell nuclei[J].Biol Repred,2000,63:1034-1040.
  • 5Santos F,Dean W.Epigenetie reprogramming during early development in mammals[J].Reproduction,2004,147:643-651.
  • 6Beaujean N,Taylor J,Garden J,et al.Effect of limited DNA methylation reprogramming in the normal sheep embryo on somatic cell nuclear transfer[J].Biol Reprod,2004,71:185-193.
  • 7Shi W,Dirim F,Wolf E,et al.Methylation reprogramming and chromosomal aneuploidy in In Vivo fertilized and cloned rabbit preimplantation embryos[J].Biol Reprod,2004,71:340-347.
  • 8Dean W,Santoa F,Stojkovic M,et al.Conservation of methylation reprogramming in mammalian development:aberrant reprogramming in cloned embryos[J].PNAS,2001,98:13734-13738.
  • 9Beaujean N,Hartshorne G,Cavilla J,et al.Non-conservation of mammalian preimplantation methylation dynamics[J].Curr Biol,2004,14:R266-R267.
  • 10Kowabara M,Wakai T,Yamanaka K I,et al.Caffine promotes premature chromosome condensation formation and in vitro development in porcine reconstructed embryos via a high level of maturation promoting factor activity during nuclear transfer[J].Reproduction,2005,130:351-357.

同被引文献22

  • 1蒋晓明,王锋.成熟促进因子对克隆重构胚核重编程的调控[J].四川动物,2004,23(4):397-400. 被引量：3
  • 2曹素英,韩建永,李建国.哺乳动物体细胞克隆后生重新编程有关机理研究进展[J].中国畜牧兽医,2005,32(2):33-36. 被引量：1
  • 3李雁,冯云,孙贻娟.体细胞核移植后核重编程的影响因素[J].生命科学,2006,18(4):355-360. 被引量：6
  • 4张力,韩树标,李跃民.动物体细胞核移植后核重编程可能的机制[J].湖北畜牧兽医,2007,28(4):16-18. 被引量：1
  • 5Borkignon V,Clarke H J,Smith L C. Factors controlling the loss of immunoreactive somatic histone H1 from blastomete nuclei in oocyte cytoplasm:a potential marker of nuclear reprogramming[J].Dev Biol, 2001,233 : 192-203.
  • 6Wakayama T, Perry A C, Zuecotti M, et al. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei[J]. Nature, 1998,394 : 369-374.
  • 7Mann M R,Chung Y G, Nolen L D, et al. Disruption of imprinted gene methylation and expression in cloned preimplantation stage mouse embryos[J]. Biology of Reproduction, 2003,69 (3) : 902-914.
  • 8Cezar G G,Bartolomei M S, Forsberg E J,et al. Genome wide epigenetic alterations in cloned bovine fetuses[J].Biology of Reproduction,2003,68(3) :1009-1014.
  • 9Enright B P,Jeong B S, Yang X, et al. Epigenetic characteristics of bovine donor cells for nuclear transfer: levels of histone acetylation[J].Biol Reprod, 2003,69 : 1525-1530.
  • 10Moon J H,Jee B C,Ku S Y,et al. Spindle position and their distribution in in vivo and in vitro matured mouse oocytes[J].Hum Reproduction, 2005,20(8) : 2207-2210.

引证文献2

二级引证文献1

中国畜牧杂志
2007年 第11期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部