206例药物性眼部损害文献分析

Drug-induced Impairments of Eyes:Literature Review of 206 Cases

目的:探讨药物性眼部损害的特点。方法:对1998年1月～2005年12月国内医药学术期刊报道的206例有关药物性眼部损害进行统计、分析。结果:诱发眼部损害的药物以抗感染类、激素类、中枢神经系统类药物所占比例较大;眼部损害临床主要表现为青光眼、角膜炎、巩膜炎、视网膜病变、前房出血、干眼症、角膜上皮损害以及视力障碍等。结论:药物性眼部损害轻者视力下降,重者可致失明,应引起医务人员重视。

OBJECTIVE：To discuss the characteristics of drug -induced eye impairment.METHODS：206 cases of drug-induced eye impairment reported in internal medical journals published from Jan. 1998 to Dec .2005 were analyzed statistically. RESULTS ： The drug - induced eye impairment was mostly induced by anti - infective drugs, hormones, nervous system drugs. The impairment was manifested predominantly by glaucoma, keratitis, scteritis; retinopathy, hyphema, xeroma, damage of corneal epithelium and visual disorder etc .CONCLUSION： Clinicians should pay great attention to the drug- induced eye impairment for it can lead to a decline in eyesight or even loss of eyesight.