真菌中的群体感应系统

Quorum Sensing in Fungi

以胞间通讯信号分子介导的细菌群体感应参与细菌多种生理功能的调控是非常普遍的。近年的研究表明,真菌中也存在类似于细菌群体感应信号分子的调节分子,并且介导着真菌某些生理行为的调节。这一过程也称为真菌的群体感应系统。文中简要介绍真菌群体感应系统的研究进展,并讨论了真菌群体感应系统作为抗真菌感染靶点的可能性。

Involvements of bacterial quorum-sensing in regulations of diverse responses are common in bacteria. Recently, it has become apparent that fungi, like bacteria, also has specific quorum sensing molecules and use quorum sensing to regulate some popalation-level behaviors of fungi. The recent progress on quorum sousing in fungi is described and the possibility of taking fungal quorum-sonsing as potential targets for antifungal therapies is discussed in the present paper.