赖特综合征临床及相关因素分析

Analysis of clinical and related factors on Reiter＇s syndrome

目的 探讨赖特综合征的病因、临床特点、治疗方法及相关因素。方法 对9例赖特综合征患者的临床资料结合文献进行分析讨论。结果 赖特综合征好发男性青年，与感染有关，有HLA-B27抗体的强烈表达。控制感染后经非甾体类药物、强的松、甲氨喋呤等治疗后，均能达到临床缓解。结论 赖特综合征是病原体感染诱发的自身免疫性疾病，一般预后良好。

Objective To discuss etiology,therapy and related factors of Reiter＇s syndrome. Methods Clinical data of nine cases of Reiter＇s syndrome patients was debated and analyzed. Results Male youth were prone to be the victim of Reiter＇s syndrome,and this syndrome was related to infection,but it would be obviously shown in the people who had HLAB27 antibody. After infection was under control, patients would be relieved on average from the disease by means of drug combination of NSAIDs,prednisone and methotrexate. Conclusion Reiter＇s syndrome is a pathogen infection-induced autoimmune disease. Once healed,the patients will be in relatively good physical condition.