No期食管鳞癌根治术后预后因素的Cox回归分析

Cox regression analysis of the prognostic factors in patients with N0 esophageal squamous carcinoma after radical surgery

目的:探讨No期食管鳞癌术后生存率的影响因素。方法:选择10个可能对术后预后产生影响的研究因素,通过Cox比例风险模型进行多因素分析,对我院1998年8月～2001年8月间的98例No期食管鳞癌术后患者预后进行研究。结果:全组1、3、5年生存率分别为95.92%、85.71%、81.63%。结论:Cox多因素分析显示,影响预后的独立因素是肿瘤浸润深度(T分期),肿瘤分化分级。

Objective： To study the prognostic factors affected the survival rate in patients with No esophageal squamous carcinoma after radical surgery. Methods： Total of 98 patients with No esophageal squamous carcinoma after radical surgery from 1997 to 2001were enrolled and 10 variables were studied by Cox regression analysis. Results： Cumulative survival rates at 1,3 and 5 years were 95.92%, 85.71% and 81.63%. In Cox model ,2 independent factors were linked with survival rate included depth of invasion and differentiation of tumor. Conclusion ： The prognostic factors in patients with Noesophageal squamous carcinoma after radical surgery are depth of invasion and differentiation of tumor.