1-苯基-3-芳基-4-甲酰基吡唑衍生物的合成及其荧光性能

Synthesis of 1-Phenyl-3-arylpyrazole-4-aldehyde Hydrazone Derivatives and Their Fluorescent Properties

以苯肼和4-取代苯乙酮(1a～1d)为原料,经过缩合,再与Vilsmeier-Haak试剂反应合环,制得1-苯基-3-芳基-4-甲酰基吡唑(3a～3d),将其与2-肼基-4/6-取代苯并噻唑(4a～4f)反应,合成一系列新化合物1-苯基-3-芳基-吡唑-4-醛[N-(4/6-取代苯并噻唑-2-基)]腙5～8.所有新化合物的结构均经IR,1H NMR,MS谱和元素分析证实.对化合物5～8的荧光进行了测定,结果显示这些化合物具有荧光特性,并探讨了化合物的结构对荧光性能的影响.

By the condensation of 4-substituted acetophenones （1a-1d） with benzene hydrazine and subsequent reaction with Vilsmeier-Haak reagent, 1-phenyl-3-aryl-4-formylpyrazoles （3a-3d） were obtained. Then they reacted with 2-hydrazino-4/6-substituted benzothiazoles （4a-4f） and produced a series of novel 1-phenyl-3-arylpyrazole-4-aldehyde N-（4/6-substituted benzothiazol-2-yl） hydrazones 5-8. Their structures were established on the basis of IR, ^1H NMR, MS spectra and elemental analysis. The fluorescent spectra of compounds 5-8 were detected and showed that they had fluorescence. The effect of the structure of the compound on fluorescent properties was also discussed.