摘要
以苯肼和4-取代苯乙酮(1a~1d)为原料,经过缩合,再与Vilsmeier-Haak试剂反应合环,制得1-苯基-3-芳基-4-甲酰基吡唑(3a~3d),将其与2-肼基-4/6-取代苯并噻唑(4a~4f)反应,合成一系列新化合物1-苯基-3-芳基-吡唑-4-醛[N-(4/6-取代苯并噻唑-2-基)]腙5~8.所有新化合物的结构均经IR,1H NMR,MS谱和元素分析证实.对化合物5~8的荧光进行了测定,结果显示这些化合物具有荧光特性,并探讨了化合物的结构对荧光性能的影响.
By the condensation of 4-substituted acetophenones (1a-1d) with benzene hydrazine and subsequent reaction with Vilsmeier-Haak reagent, 1-phenyl-3-aryl-4-formylpyrazoles (3a-3d) were obtained. Then they reacted with 2-hydrazino-4/6-substituted benzothiazoles (4a-4f) and produced a series of novel 1-phenyl-3-arylpyrazole-4-aldehyde N-(4/6-substituted benzothiazol-2-yl) hydrazones 5-8. Their structures were established on the basis of IR, ^1H NMR, MS spectra and elemental analysis. The fluorescent spectra of compounds 5-8 were detected and showed that they had fluorescence. The effect of the structure of the compound on fluorescent properties was also discussed.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2007年第6期790-794,共5页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(Nos.29962002
20462006)资助项目.
关键词
苯肼
苯并噻唑肼
4-甲酰基吡唑
荧光性能
benzene hydrazine
benzothiazole
4-formylpyrazole
fluorescent property