郑州地区668例婴幼儿下呼吸道病毒感染的流行病学研究

An Epidemiological Study on 668 Infants with Lower Respiratory Tract Infections Caused by Viruses in

为了探讨郑州地区下呼吸道病毒感染的规律，作者从１９９２年１２月～１９９５年３月连续三年冬春季，对病程在一周以内的下呼吸道感染患儿进行鼻咽部分泌物脱落细胞内常见病毒抗原检测。结果为：６６８例患儿有关病毒抗原阳性者３６６例，阳性率为５４．８％。在阳性病例中，合胞病毒占３３．９％，流感病毒占２７．３％，副流感病毒占１５．０％，两种以上病毒混合感染占２３．８％。结果提示婴幼儿下呼吸道感染有一半以上是病毒感染所致。每年流行的病毒种类不同，１９９２年冬至１９９３年春以流感病毒为主，占当年度病毒感染的６１．２％；１９９３年冬至１９９４年春以呼吸道合胞病毒为主，占８４．０％；１９９４年冬至１９９５年春以副流感病毒为主，占４９．０％。

From December 1992 to March 1995 we studied the common respiratory virus antigens in nasopharyngeal sloughed cells from infants, who suffered from lower respiratory tract infections within the first week after onset. Among these 668 cases there were 366 cases (54.8%)with positive antigen detection, suggesting that more than half of the patients were caused by viral infections. Among these respiratory viruses, 33 9% of the cases were infected by respiratory syncytial virus, 27 3% by influenza virus and 15.0% by parainfluenza virus. During the winter in 1992 to the spring in 1993, influenza virus was predominant 61.2% in this period; during the winter in 1993 to the spring in 1994, respiratory syncytial virus (83.96%) was dominant and during the winter in 1994 to the spring in 1995, parainfluenza virus(49.00%).