摘要
抗肿瘤药物新靶点包括蛋白激酶、细胞周期和凋亡调节基因、蛋白法尼基转移酶、组蛋白去乙酰化酶和端粒酶。综述这些靶点及其相应药物近年来的研究进展。
This review presents a comprehensive summary and discussion on the most important targets currently attracting a great deal of interest in contemporary anticancer drug design and discovery, including protein kinases, the cell cycle regulators, apoptosis modulators, FTase, histone deacetylase and telomerase.
出处
《药学进展》
CAS
2007年第6期247-253,共7页
Progress in Pharmaceutical Sciences
关键词
肿瘤
抗肿瘤药物
靶点
Turnout
Anticancer drug
Target
