摘要
研究了37例梗阻性黄疸(A组)和90例单纯胆囊结石(D组)IL-2和sIL-2R,讨论梗阻性黄疸患者BTP、PVBF与IL-2、sIL-2R的关系。A组分为急诊手术(B组)和择期手术(C组)。结果显示:1.梗阻性黄疸患者IL-2显著低于胆囊结石,恶性梗阻、良性梗阻和胆囊结石之间IL-2比较有极显著差异(P<0.01)。2.A～C组术前sIL-2R显著高于术后8～12天(P<0.01),D组术前sIL-2R显著高于术后3～7天(P<0.01)。在术前外周血和门静脉血中,B组sIL-2R显著高于A、C和D组。3.BTP与IL-2呈负相关,与sIL-2R呈正相关。PVBF与IL-2呈正相关,与sIL-2R呈负相关。因此认为sIL-2R变化可作为疾病严重程度的预后指标。
Interleukin-2(IL-2)and soluble interleukin-2 receptor (sIL-2R) were studied in 37 cases with obstructive jaundice (group A)and 90 patients with simple gallstones (group D). Relationships between biliary tract pressure(BTP),portal vein blood flow (PVBF)and IL-2,sIL-2R were discussed. The results showed: 1.IL-2 was lower obviously in obstructive jaundice group than that of gallstone group. IL-2, compared with malignant or benign obstruciton and gallstones patients,was remarkedly different(P< 0. 01)). 2. sIL-2R was higher significantly in pre-operation than that of post-operation 8-12 days from group A to group C(P<0. 01) ,sIL-2R was higher in pre-operation than that of post-operation 3 - 7 days in group D(P<0. 01). sIL-2R was higher in group B than that of group A,group C and group D both in peripheral vein blood and portal vein blood. 3. Regressive analysis of BTP with IL-2 was negatively related and BTP with sIL-2R was positively related(P<0. 01). Regressive analysis of PVBF with IL-2 was positively related and PVBF with sIL-2R was negatively related (P<0. 01). sIL-2R may be indexes of the severity of obstructive jaundice.
出处
《天津医药》
CAS
1997年第1期18-21,共4页
Tianjin Medical Journal
关键词
梗阻性黄疸
胆道压力
白细胞介素
免疫功能
obstructive jaundice biliary tract pressure portal yein blood flow inter-leukin-2 soluble interleukin-2 receptor
