梗阻性黄疸患者机体免疫功能变化及转归研究——Ⅳ.精氨酸对梗阻性黄疸细胞免疫调节

Changes and Inturns of Humoral and Cellular Immunity with Obstructive Jaundice Ⅳ. Regulation with Arginine in Obstructive Jaundice

50例梗阻性黄疸分为非精氨酸组(A组)和精氨酸组(B组),研究精氨酸对梗阻性黄疸细胞免疫调节作用。结果显示,无论是A组还是B组,手术后CD_3^+、CD_4^+显著高于手术前,sIL-2R显著低于手术前(P<0.01)。说明解除胆道梗阻后,细胞免疫功能改善,尤其B组更明显。无论是手术前,还是手术后,B组CD_3^+、CD_4^+显著高于A组,sIL-2R显著低于A组(P<0.01),表明精氨酸有改善梗阻性黄疸细胞免疫功能。

Fifty patients with obstructive jaundice were devided into non-arginine group (group A)and arginine group (group B). Regulation with arginine has been studied in obstructive jaundice. The re- suits showed that CD3+,CD4+ were higher post-operatively than those of preoperation, and sIL-2R was lower post-operatively than that of preoperation in both groups A and B. It was indicated that cellular immunity functions were improved after relieving biliary obstruction. CD3+,CD4+ were higher obviously in group B than those of group A,and sIL-2R was lower significantly in group B than that of group A both in pre-and post-operation periods (P<0. 01). It was showed that cellular immunity function was improved by arginine in obstructive jaundice patients.