口服奥硝唑治疗急性冠周炎的临床疗效评价

Evaluation of the Effects of Oral Ornidazle on Acute Pericoronnitis

目的临床观察奥硝唑治疗急性冠周炎的疗效.方法应用口服奥硝唑治疗37例急性冠周炎患者,以甲硝唑作为对照,检测了两组治疗前后盲袋内厌氧菌的变化及临床疗效.结果奥硝唑组和甲硝唑组对主要厌氧菌的杀菌率分别为91.7%和60.9%,对主要厌氧菌的抑菌率分别94.5%和68.2%(P<0.01).奥硝唑组治疗急性冠周炎的临床疗效(有效率81.1%)也优于甲硝唑组(有效率38.7%).结论奥硝唑应成为急性冠周炎患者全身给药的首选药物.

Objective Clinically observe the effects of Ornidazle on acute pericoronnitis patients. Meth- ods 37 cases with acute pericoronnitis, who took Ornidazle orally, were compared with the control group, who took Metronidazole, to detect the changes of anaerobic bacteria in blind - sack and the clinical effects before and after treatment in the two groups. Results The bactericidal rate of Ornidazle group and Metronidazole group a-gainst anaerobic bacteria were 91.7% and 60.9%, respectively, and the bacteria controlling rate of the two groups were 94. 5% and 68.2%, respectively （P 〈0.01）. The treatment effect of Ornidazle group （81.1%） was better than that of the Metronidazole group （38.7%）. Conclusion Ornidazle should become the priority medicine for an acute pericoronnitis patient.