50例原发胃肠道非霍奇金淋巴瘤临床病理与预后的关系

Relationship between prognosis and clinicopathologic features of primary gastrointestinal non Hodgkin′s lymphoma in 50 cases

作者对５０例原发胃肠道非霍奇金淋巴瘤（ＧＩ－ＮＨＬ）的预后因素进行了分析。结果显示：临床分期Ⅰ、Ⅱ期病人预后明显优于Ⅳ期，５年存活率分别为６８．９％，８．３％（Ｐ＜０．０１）。在Ⅳ期病人中手术切除肿块者优于未切除者（Ｐ＜０．０５）。病理分类低度恶性者５年存活率略高于中／高度恶性者，分别为７５％，４０．８％（ｘ２＝１．７３５Ｐ＜０．２）。性别、年龄与预后无关。提示早期诊断、积极手术治疗是原发ＧＩ－ＮＨＬ长期生存的关键所在。

This paper evaluated the prognostic factors in 50 patients with primary gastrointestinal non Hodgkin′s lymphoma.The result showed that the prognosis of patients in stage Ⅰ and Ⅱ was much better than those in stage Ⅳ;five year survival rates were 68 9% and 8 3% respectively ( P <0 01).In the patients of stage Ⅳ surgical resection had a better survival rate, compared with unresection ones ( P <0 05).Five year survival rate of low grade malignant group (according to pathological classification) was a little higher than that of intermediate/high grade malignant groups,being 75% and 40 8% respectively ( x 2=1 735, P <0 2). Sex and age had no relation to prognosis.The result above indicates that earlier diagnosis and surgical resection are essential in the treatment of patients with primary gestrointestinal non Hodgkin′s lymphoma.