急性横贯性脊髓炎新诊断标准和分类的临床应用

Clinical applications of the novel diagnostic criteria and classification of acute transverse myelitis

目的探讨急性横贯性脊髓炎(ATM)新诊断标准和分类的临床应用。方法对33例ATM患者的临床资料进行回顾性分析,并与JohesHopkins医院神经内科制定的ATM诊断标准和分类方法进行对照。结果(1)本组患者均为急性起病,其中有6例起病时伴发热,全部病例均出现双下肢瘫痪,病变累及胸髓最多(29例);(2)与新标准对照,10例符合新标准分型中的伴发感染相关的ATM,7例符合与多发性硬化相关的ATM;1例符合缺血所致的ATM。结论ATM具有起病快,病因复杂的特点,新标准可能有助于ATM的诊断、疾病分类和发病机制的探讨。

Objective To study clinical applications of the novel diagnostic criteria and classification of acute transverse myelitis （ATM）. Methods Retrospective analysis of the clinical data in 33 cases with ATM was carried out according to diagnostic criteria and classification of ATM formulated by Department of Neurology of Johes Hopkins Hospital. Results （ 1 ） All of these cases were acute onset and combined fever in 6 patients. All cases manifested bilateral paraparesis or paraplegia. 29 cases were involved in thoracic cord. （2）As compared to the new criteria, 10 cases were ATM accompanied with infection;7 patients were ATM related to multiple sclerosis; 1 patient was ATM caused by ischemic lesions. Conclusions The characteristics of ATM are acute onset and complicated etiology. The novel criteria may be helpful to diagnosis, disease nosology and studies of its pathogenesis.