病理性近视眼底荧光造影分析

Analysis of fundus fluorescein angiography features in pathologic myopia

目的:观察病理性近视的荧光素眼底血管造影(FFA)的特征。方法:选择-8.00D以上病理性近视患者共80例106眼行FFA检查,根据造影表现结合眼科常规检查情况进行分析。结果:造影显示视神经乳头出现异常荧光者21眼(19.8%)。视网膜出现局灶性窗口样荧光32眼(30.2%),局灶性墨汁样渗漏荧光20眼(18.9%),局灶性荧光遮蔽18眼(17.0%)。黄斑区的局灶性荧光遮蔽15眼(14.2%),局灶性荧光渗漏12眼(11.3%)。视网膜血管的异常荧光共10眼(9.4%)。视网膜下脉络膜新生血管25眼(23.6%),发生在黄斑区、后极部和周边部,呈单一或多发病灶。结论:病理性近视视网膜脉络膜呈现复杂多样的病变特征,尤其是脉络膜新生血管多发危害大,FFA为临床干预治疗提供依据。

AIM： To investigate the fundus features of pathologic myopia （PM） by using fundus fluorescein angiography （FFA）. METHODS： A total of 106 eyes of 80 patients with refractive error higher than -8.00D were performed with FFA. Photos of FFA were analyzed and compared with the outcome of routine examination. RESULTS： Using FFA, the optic papilla were found to appear as hypoor hyperfluorescence in 21eyes （19.8%）. Window defects appeared in 32 eyes （30.2%）, fluorescein leakage in 20 eyes （18.9%） and masking within the retina in 18 eyes （17.0%）. Rfteen eyes （14.2%） showed local masking at the macula and 12 eyes （11.3%） had fluorescein leakage. Vascular abnormalities were found in 10 eyes （9.4%）, and 25 eyes （23.6%） were combined with submacular chordidal neovescularization （CNV） as single or multiple focus spreading on the macula, posterior pole and the peripheral retina. CONCLUSION： Chorioretinal eaxminations of pathologic myopia show complicated features, and the multiple CNV causes severe damage to the visual function. FFA can provide the evidences for the clinical intervention.