摘要
目的低剂量阿托伐他汀对冠心病患者血脂及血清C-反应蛋白浓度的影响。方法将98例稳定性冠心病伴高脂血症患者随机分为治疗组53例和对照组45例,在常规治疗的基础上治疗组口服阿托伐他汀(5mg/d),对照组不加降脂药物,疗程均为6w。结果疗程结束后治疗组血脂指标及C-反应蛋白(CRP)改善情况均明显优于对照组,两组间结果具有显著性差异(p<0.05)。结论较低剂量阿托伐他汀对冠心病患者具有良好的降脂效应,且能有效降低患者的CRP,安全性良好。
Objective To research the influence of the low dose atorvastatin on blood lipid and C - reactive protein （CRP） in elderly coronary heart disease. Methods 98 patients of stable coronary heart disease with hyperllpidemia were diviced to the treated group and the control group. The treated group was oral administration with atorvastatin for 6 weeks, measuring their blood lipid and blood CRP before and after treatment, then to analyse them with statistics. Results After 6 weeks of treatment, the patients＇ plasma levels of TC, TG, LDL - C and CRP were significantly decreased （p 〈 0.05 ）. Condusion The low dose atorvastatin can reduce the blood liqid and CRP safely of elderly patients of stable coronary heart disease with hyperlipidemia.
出处
《现代医院》
2007年第6期42-43,共2页
Modern Hospitals
关键词
阿托伐他汀
血脂
C-反应蛋白
冠心病
atorvastatin, blood liqid, C - reactive protein, elderly coronary heart disease
