肺气虚证模型大鼠的影像学表现

The image expression of rats with insufficiency of the lung-qi

目的探讨肺气虚证模型大鼠的影像学变化。方法用两次气管内注入脂多糖(LPS)及熏香烟4周的复合刺激法建立肺气虚证模型大鼠,4周后各组摄片,并观察一般状况、呼吸频率、质量改变情况及病理变化。结果呼吸频率两组相比,差异有高度统计意义(P<0.01);横膈前肋、横膈后肋积分及肋间隙两组相比,差异有高度统计意义(P<0.01)。结论肺气虚证大鼠有明显的肺气肿影像学表现。

Objective：To study the image changes of the rats with insufficiency of the lung-qi. Methods： The rat models with insufficiency of the hng-qi were established by intratracheal instillation of lipopolysaccharide（LPS） twice and exposed to cigarette smoke and they were photographed after 4 weeks. Results： The breath frequency, the scores of diaphragmatic anterior ribs and posterior ribs, spatium intercostale had obvious difference between two groups （ P 〈 0. 01 ）. Conclusion ： The rats with insufficiency of the lung-qi shows obvious image expression of pulmonary emphysema.