回归平衡胶囊治疗大耳白兔性早熟的药效学研究

Study on Pharmacodynamics of Huigui Pingheng Capsules in the Therapy of Sexual Precocity of Special Rabbits

目的探究性早熟动物模型的制备及观察回归平衡胶囊对性早熟大耳白兔的药效学作用。方法用鸡胚粉喂养大耳白幼兔制备性早熟模型;用回归平衡胶囊对性早熟幼兔进行灌胃给药1个月后,检查回归平衡胶囊对幼兔血清的性激素E2,PROG,TESTO,LH,FSH等的影响,进行组间差异显著性比较。结果实验给药组的性激素水平较对照组有显著降低。结论回归平衡胶囊对性早熟大耳白兔有确切的治疗作用。

Objective To study the model of the sexual precocious animal and to observe the pharmacodynamics of Huigui Pingheng capsules in sexual precocity of special rabbits. Methods The experimental sexual precocious model of special rabbits was made by feeding in stomach with chick embryo powder. These special rabbits in the experimental group were given with Huigui Pingheng capsules for one month. To check changes of the blood biochemical criterion of infant rabbits such as levels of hormone E2, PROG,TESTO, LH, FSH and compare with the normal control group. Results Most of the levels of blood hormone histology criterions of sexual precocity of special rabbits in the experimental groups were significantly reduced. Conclusion Sexual precocity of special rabbits can be effectively treated with Huigui Pingheng capsules.