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哺乳动物的miRNA研究 被引量：1

Advances of mammalian miRNA research
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摘要 微小RNA(microRNA,miRNA)是新近发现的一类重要非编码调控RNA,以转录或转录后水平调节方式参与哺乳动物发育(细胞生长、分化、凋亡)、免疫调节及疾病发生等过程。就miRNA的形成及作用机制,哺乳动物中miRNA发现策略、靶位点的识别,miRNA功能研究进行综述,为类似研究提供参考。 As one of lately-developed non-coding RNA molecule, miRNAs （microRNAs） play crucial roles during the mammalian embryo development （including cell growth, differentiation and apoptosis）, immunity modu-lation and disease cause, by means of transcriptional or post- transcriptional regulation. The formation and molecu-lar mechanism of miRNA, the discovery and target identification of mi RNA, the latest function studies of miRNA were reviewed, so as to offer useful suggestion for miRNA research in mammals.
作者 程会军 张定校 樊斌
机构地区 华中农业大学动物分子生物学与育种实验室
出处 《生物学杂志》 CAS CSCD 2007年第3期1-5,共5页 Journal of Biology
基金 国家自然科学基金(30300250)
关键词 MIRNA 作用机制 功能 哺乳动物 miRNA molecular mechanism function mammalian
分类号 Q522 [生物学—生物化学]
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参考文献35

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同被引文献14

  • 1宋薇,刘精东.高尿酸血症和痛风的流行病学及影响因素研究进展[J].江西医药,2013,48(5):459-462. 被引量：49
  • 2李俊,梁君山,周爱武,陈敏珠,徐叔云.白芍总甙对B淋巴细胞增殖和白介素1生成的调节作用[J].中国药理学与毒理学杂志,1994,8(1):53-55. 被引量：61
  • 3顿耀艳,袁丁,张长城.大鼠滑膜细胞原代培养的研究[J].实用医学进修杂志,2007,35(2):126-128. 被引量：4
  • 4熊建文,肖化,张镇西.MTT法和CCK-8法检测细胞活性之测试条件比较[J].激光生物学报,2007,16(5):559-562. 被引量：143
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  • 6宋震坤.痛风宁对痛风性关节炎滑膜细胞环氧化酶和细胞因子影响的实验研究[D].杭州:浙江中医学院,2002:3.
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生物学杂志
2007年 第3期

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