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维A酸受体在卵巢癌中的表达 被引量：2

Expression of retinoid receptors in ovarian cancer
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摘要 维A酸类化合物对恶性肿瘤的预防和治疗作用越来越受到人们的关注,它对肿瘤细胞具有促进凋亡、抑制生长、诱导分化等作用,这均与细胞核内维A酸受体表达有关。现就维A酸受体在卵巢癌中的表达作一综述。 Ovarian cancer is highly lethal despite multiple therapies, and new therapies are therefore needed. Retinoids are potential anticancer drugs that can promote apoptosis, inhibit growth and induce differentiation in cancer cells, and all these functions are regulated by the expression of retinoid receptors. Herein the recent researches on the expression of retinoid receptors in ovarian cancer are reviewed.
作者 刘爽 刘琦
机构地区 南京军区南京总医院南方医科大学南京临床医学院妇产科
出处 《医学研究生学报》 CAS 2007年第6期648-650,655,共4页 Journal of Medical Postgraduates
基金 全国博士后科学基金资助项目(批准号:2005038578)
关键词 维A酸类化合物 维A酸受体 卵巢癌 Retinoids Retinoid receptors Ovarian cancer
分类号 R737.31 [医药卫生—肿瘤]
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  • 1Zhang Dong-mei,Holmes W F,Wu Shu-jian,et al.Retinoids and ovarian cancer[ J ].J Cell Physiol,2000,185:1-20.
  • 2Guruswamy S,Lightfoot S,Michael A G,et al.Effects of retinoids on cancerous phenotype and apoptosis in organotypic cultures of ovarian tumors[ J ].J Natl Cancer Inst,2001,93:516-525.
  • 3Miwa I,Suzuki S.An improved quantitative assay of glycogen in erythrocytes[ J].Ann Clin Biochem,2002,39:612-613.
  • 4Gomez-Lechon M J,Ponsoda X,Castell J V.A microassay for measuring glycogen in 96-well-cultured cells[J].Anal Biochem,1996,236 (2):296-301.
  • 5Khan SA, Wingard JR. Infection and mucosal injury in cancer treatment[ J]. J Natl Cancer Inst Monogr, 2001,29:31-36.
  • 6Symonds RP. Treatment-induced mucositis: an old problem with new remedies[J]. Br J Cancer, 1998, 77(10): 1689-1695.
  • 7Baumgart DC, Dignass AU. Intestinal barrier function[ J ]. Curr Opin Clin Nutr Metab Care, 2002, 5(6): 685-694.
  • 8Unno N,Fink MP. Intestinal epithelial hyperpermeability. Mechanisms and relevance to disease [ J ]. Gastroenterol Clin North Am, 1998, 27(2): 289-307.
  • 9de Witt RC, Kudsk KA. The gut' s role in metabolism, mucosal barrier function, and gut immunology[ J]. Infect Dis Clin North Am, 1999, 13(2): 465-481.
  • 10Johnston SD, Smye M, Watson RP. Intestinal permeability tests in coeliac disease[J]. Clin Lab, 2001,47(3-4): 143-150.

共引文献26

同被引文献37

  • 1Morkve O, Learun OD. Flow cytometric measurement of p53 protein expression and DNA content in paraffin-embedded tissue from bronchial carcinomas [ J]. Cytometry, 1991, 12(5) :438-444.
  • 2Wittekind C, Neid M. Cancer invasion and metastasis [ J ]. Oncology, 2005, 69 (1):14-16.
  • 3Imai T, Horiuchi A, Shiozawa T, et al. Elevated expression of Ecadherin and alpha-, beta-, and gamma-catenins in metastatic lesions compared with primary epithelial ovarian carcinomas [ J ].Hum Pathol, 2004, 35(12) :1469-1476.
  • 4Faleiro-Bodrigues C, Macedo-Pinto I, Pereira D, et al. Prognostic value of E-cadherin immunoexpression in patients with primary ovarian carcinomas[ J]. Ann Oncol,2004, 15(10) :1535-1542.
  • 5Ara C, Devirgiliis LC, Massimi M. Influence of retinoic acid on adhesion complexes in human hepatoma cells: a clue to its antiproliferative effects [ J ]. Cell Commun Adhes, 2004, 11 ( 1 ) : 13- 23.
  • 6Davidson B, Shafat I, Risberg B, et al. Heparanase expression correlates with poor survival in metastatic ovarian carcinoma [ J ]. Gynecol Oncol, 2007,104(2) :311-319.
  • 7He X, Brenchley PE, Jayson GC, et al. Hypoxia increases heparanase-dependent tumor cell invasion, which can,be inhibited by antiheparanase antibodies[J]. Cancer Res, 2004, 64 ( 11 ) : 3928-3933.
  • 8Hoffmann S, Rockenstein A, Ramaswamy A, et at. Retinoic acid inhibits angiogenesis and tumor growth of thyroid cancer cells [J]. Mol Cell Endocrinol, 2007, 264(2) :74-81.
  • 9Pal S, Iruelar Arispe ML, Harvey VS, et al. Retinoic acid selectively inhibits the vascular permenhilizing effect of VPF/VEGF, an early step in the angiogenic cascade [ J ]. Microvasc Res, 2000, 60(2) :112-120.
  • 10Simizu S,Ishida K,Wierzba MK,et al.Secretion of heparanase protein is regulated by glycosylation in human tumor cell lines[J].J Biol Chem,2004,279(4):2697-2703.

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医学研究生学报
2007年 第6期

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