羊水量与胎儿血流动力学相关性的研究

Correlation study on the amounts of amniotic fluid and hemodynamics in fetuses

目的应用彩色多普勒超声研究不同羊水量胎儿脐动脉及大脑中动脉的血流速度波形,分析两者间的关系及围生儿结局。方法对148例晚期妊娠妇女进行胎儿脐动脉及大脑中动脉的血流速度波形检查,计算收缩期峰值流速与舒张末期流速比值、阻力指数、大脑中动脉与脐动脉之间的阻力指数比值,随访围生儿预后。结果胎儿脐动脉收缩期峰值流速与舒张末期流速比值≥3及大脑中动脉收缩期峰值流速与舒张末期流速比值≤4者,在羊水过少组较对照组明显增多(P<0．05),且该组胎儿易发生不良围生儿结局。结论对胎儿脐动脉、大脑中动脉血流速度波形进行检测,可监护胎儿宫内状况,并对妊娠结局有预测价值。

Objective To investigate the flow velocity waveforms （FVWs） in umbilical arteries （UA） and middle cerebral arteries （MCA） in various amounts of amniotic fluid by colored Doppler ultrasonography and analyze the correlation between such changes and perinatal outcomes. Methods One hundred and forty-eight women in their third trimester of pregnancy were examined by colored Doppler ultrasonography for their fetal blood FVWs of the UA and MCA, systolic/diastolic ratio （S/D）, resistances index （RI） and RIMCA/RIUA values. Perinatal prognosis was followed up. Results It showed a significant increase in S/D ratio （S/D≥3） of UA and S/D≤4 of MCA in oligoamnios and an adverse perinatal outcome would likely occur in this group. Conclusions This study shows that examination of fetal blood FVWs in UA and MCA is a valuable method for fetal surveillance and useful in predicting fetal prognosis.