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H pylori infection in patients with Behcet's disease 被引量:3

H pylori infection in patients with Behcet’s disease
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摘要 AIM:To evaluate endoscopic findings and the prevalence of H pylori in patients with Behcet's disease (BD) who have upper gastrointestinal symptoms. METHODS:The patients with BD diagnosed according to the International Study Group and followed up in the Department of Dermatology and other related departments and who had any upper gastrointestinal complaints,were included in this study. Forty-five patients with BD and 40 patients in the control group were evaluated by upper gastrointestinal endoscopy and two biopsied specimens were taken during endoscopy for H pylori . A two-week triple therapy for H pylori eradication was administered to H pylori positive patients. Two months after the treatment,the patients were evaluated by urea-breath test for eradication control. RESULTS:Patients with BD had a mean age of 36.2 ± 11.4 years (18-67 years). The mean follow-up time was 35 ± 14 mo (16-84 mo). Aphthous or deep ulcer in esophagus,stomach and duodenum had never been confirmed by endoscopic examination. Most gastric lesions were gastric erosion (40%) and the most duodenal lesions were duodenitis (17.5%) in two groups. H pylori was positive in 33 patients (73.3%) with BD. The two-week triple eradication therapy was successful in 75% of the patients. There was no difference between the groups in respect to prevalence of H pylori (73.3% vs 75%,P > 0.05),and eradication rate (75% vs 70%,P > 0.05). CONCLUSION:Endoscopic findings,eradication rate and prevalence of H pylori were similar in patients withBD and control group. AIM:To evaluate endoscopic findings and the prevalence of H pylori in patients with Behcet's disease (BD) who have upper gastrointestinal symptoms. METHODS:The patients with BD diagnosed according to the International Study Group and followed up in the Department of Dermatology and other related departments and who had any upper gastrointestinal complaints,were included in this study. Forty-five patients with BD and 40 patients in the control group were evaluated by upper gastrointestinal endoscopy and two biopsied specimens were taken during endoscopy for H pylori . A two-week triple therapy for H pylori eradication was administered to H pylori positive patients. Two months after the treatment,the patients were evaluated by urea-breath test for eradication control. RESULTS:Patients with BD had a mean age of 36.2 ± 11.4 years (18-67 years). The mean follow-up time was 35 ± 14 mo (16-84 mo). Aphthous or deep ulcer in esophagus,stomach and duodenum had never been confirmed by endoscopic examination. Most gastric lesions were gastric erosion (40%) and the most duodenal lesions were duodenitis (17.5%) in two groups. H pylori was positive in 33 patients (73.3%) with BD. The two-week triple eradication therapy was successful in 75% of the patients. There was no difference between the groups in respect to prevalence of H pylori (73.3% vs 75%,P 〉 0.05),and eradication rate (75% vs 70%,P 〉 0.05). CONCLUSION:Endoscopic findings,eradication rate and prevalence of H pylori were similar in patients withBD and control group.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第21期2983-2985,共3页 世界胃肠病学杂志(英文版)
关键词 HPYLORI Behcet's disease VASCULITIS endoscopic findings aphthous ulcer 幽门螺杆菌病 内窥镜 血管炎 白塞病 致病性
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  • 1Lai Ning-Sheng,Lai Ruay-Sheng,Tseng Kuo-Chih. High frequency of unusual gastric/duodenal ulcers in patients with Beh?et’s disease in Taiwan: a possible correlation of MHC molecules with the development of gastric/duodenal ulcers[J] 2005,Clinical Rheumatology(5):516~520
  • 2Dr. Yoh Kasahara M.D.,Shigeru Tanaka M.D.,Mikio Nishino M.D.,Hiroya Umemura M.D.,Sei Shiraha M.D.,Takeshi Kuyama M.D.. Intestinal involvement in Beh?et’s disease: Review of 136 surgical cases in the Japanese literature[J] 1981,Diseases of the Colon & Rectum(2):103~106

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  • 3Suerbaum S,Michetti P.Helicobacter pylori infection[].New England Journal of Homeopathy.2002
  • 4Marshall B J,Warren J R.Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration[].The Lancet.1984
  • 5Arnold, Isabelle C,Dehzad, Nina,Reuter, Sebastian,Martin, Helen,Becher, Burkhard,Taube, Christian,Müller, Anne.Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells[J].Journal of Clinical Investigation.2011(8)
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