不典型川崎病早期诊断相关因素的探讨

Discussion of the Early Diagnosis Factors in Atypical Kawasaki Disease

目的探讨不典型川崎病(KD)的早期诊断。方法总结1996年9月-2006年9月收住院的38例不典型川崎病病例,回顾性分析不典型KD早期表现及实验室检查指标。结果KD 80%以上的患儿有C反应蛋白升高,血沉增快,WBC升高,血红蛋白下降,白蛋白降低,血小板增高。在本组病例最早出现时间为病程的第2天至第5天。结论在临床表现条件不足时,WBC升高,血沉增快,血红蛋白下降,C反应蛋白升高,白蛋白减低,血小板增高,可用于不典型KD的早期诊断。

Objective To explore the early diagnosis of atypical Kawasaki Disease（KD）. Methods We summed up the hospitalized 38 cases of atypical Kawasaki Disease from September 1996 to September 2006, and analysed the early manifestations and laboratory target of Kawasaki Disease retrospectively. Results In more than 80% patients with Kawasaki Disease, white blood cells increased, erythrocyte sedimentation rate increased, hemoglobin decreased C-response proteins went up, the proportion of albumin increased and platelets increased also. In this group of cases, the starting time was at the 2nd day to the 5th day in course of disease. Conclusion When the clinical manifestations disappeared completely, white blood cells increased, erythrocyte sedimentation rate increased, hemoglobin decreased, C-response proteins went up, the proportion of albumin increases and platelets increased, so this could be used in the early diagnosis of atypical Kawasaki Disease （KD）.