摘要
我们在Ikeda相位重置模型的基础上,考虑异位起搏点(Ectopic Pacemaker,E)的位置及本位起搏点(Sinus Pacemaker,S)对E作用强弱的不同,建立了4个一维分段映象模型,研究心脏在S与E共同驱动下的节律运动。数值计算表明:大部分的心搏模式都是周期性的,在扰动频率和扰动强度的参数平面上具有Arnold舌头分布;异位起搏点位于心室时,有双稳态的动力学模式;在奇重置弱耦合和偶重置异位起搏点的不应期较长时,观察到临床上出现的二联律,三联律等异常心搏模式。
In this paper are proposed four heartbeat models which correspond to two different positions of the ectopic pacemaker and two coupling styles of the sinus and ectopic pacemakers. The models computed are based on the modified Ikeda phase resetting model. Most of the heartbeat modes are periodic; they exhibit "Arnold's tongue" structure in parameter plane of perturbing frequency and strength. When the ectopic pacemaker is located in the ventricle, there are bistable dynamic modes. The abnormal hearbeat rhythms of bigeminy and trigeminy in clinical medicine have been observed when coupling strength is weaker in odd resetting or refractory time is longer in even resetting.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2007年第3期509-512,共4页
Journal of Biomedical Engineering
基金
国家自然科学基金资助项目(39870233
30270340)
沈阳市科技计划资助项目(1063314-1-00)