烟雾病的临床及影像研究

Clinical and Imaging Study of Moyamoya Disease.

目的:研究烟雾病(moyamoya disease,MMD)的临床及影像学特征。方法:回顾性分析27例烟雾病,观察其临床及影像学特点。结果:本组病例多为儿童及青壮年起病,女性居多。病程为多发,主要有脑梗死、出血和短暂脑缺血发作等起病形式,临床表现为肢体麻木、无力、头痛、智力减退等症状;DSA在脑底动脉环发现血管闭塞、狭窄及烟雾状毛细血管网形成,MRA对本病有一定阳性发现。结论:对于儿童及青壮年反复发作的脑卒中患者要考虑MMD的可能,目前仍依靠数字减影血管造影确诊,MRA对本病有一定阳性发现。

Objective： To study the clinical and imaging features of moyamoya disease. Methods： 27 patients who were diagnosed moyamoya disease were investigated. The clinical representation, DSA and MRI changes were observed. Resuits： The disease primarily affects children and youth. The first symptom is often stroke, or recurrent transient ischemic attacks, frequently accompanied by weakness or paralysis affecting one side of the body, or seizures. Adults more often experience a hemorrhagic stroke than children. Individuals with this disorder may have disturbed consciousness, aphasia, sensory and cognitive impairments. DSA can find vascular occlusion in the circle of willis and blood capillary formed to compensate. MRA can help to make diagnose. Conclusion： When we meet the stroke patients in children or youth, moyamoya disease should be considered. In additional, MRA can help to find the problem, but we also need DSA to make the final diagnosis.