血管性痴呆患者脑脊液铝水平检测

Determination of CSF Aluminum Levels in Patients with Vascular Dementia

为探讨血管性痴呆（VD）与老年性痴呆（AD）在发病机制上是否有某些共同点，对50例VD患者及25例健康对照组进行脑脊液（CSF）铝水平检测。结果表明，VD组CSF铝水平为2．48±2．42μmol／L，对照组为0．53±0．61μmol／L，VD组较对照组显著增高（P＜0．001）。推测VD发病机制可能与AD有某些共同之处。

In order to explore the correlations in the pathogenesis of vascular dementia andAlzheimer's dementia. We detected the aluminum in CSF of 50 cases with vascular dementiaof cerebral infarct. The results showed that levels of aluminum in CSF with vascular demen-tia were increased as compared with the controls, mean 2. 48± 2. 42 μmol/L and 0. 53±0. 61μmol/L respectively, (P<0.001 ). These were consistent with general findings in cases ofAlzheimer's dementia. It was therefore suggested that the pathogenic process of vascular de-mentia is similar to that of vascular Alzheimer's dementia.