急性心肌梗死发病早期的血脂分析

Lipid analysis in early stage of acute myocardial infarction

目的探讨急性心肌梗死(AMI)患者发病早期的血脂水平。方法对104例AMI患者入院24h之内进行血脂测定,并与心绞痛组(CHD)、健康查体组(CON)血脂进行组间比较。对AMI组中按照不同年龄、性别、吸烟、血压、血糖进行分组,不同分组间的血脂水平分别进行比较。结果AMI发病早期TC、LDL-C水平比CHD组及CON组明显降低,AMI组和CHD组HDL-C水平均较CON组降低。AMI发病早期血脂水平在60岁以上和60岁以下、高血压病和非高血压病、糖尿病和非糖尿病之间存在显著性差异。结论AMI发病早期血脂有下降趋势,尤以TC、LDL-C为显著,不能以此延误他汀类调脂药物的早期应用。

Objective To evaluate the serum-lipid level in early stage （ ≤ 24 hours） of acute myocardial infarction （AMI）. Methods Plasma-cholesterol （TC）, triglyceride （TG）, low density lipoprotein cholesterol （LDL-C）and high density lipoprotein cholesterol （HDL-C）were measured in 104 patients with AMI. Compare the measurements with those of CHD group and CON group. All the AMI patients were divided into groups according to age, gender,smoking, blood pressure, blood glucose, and compare the serum-lipid level in groups respectively. Results Compared with CHD group and CON group, the level of TC and LDL-C in AMI group was decreased significantly. Lipid levels of AMI patients were different between middle aged and aged, hypertension and non-hypertension, diabetic mellitus and non-diabetic mellitus. Conclusion Serum-lipid level in early stage of AMI has descending tendency, especially TC and LDL-C, We can not delay the use of of statins.