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斑秃毛囊器官特异性自身免疫发病机制和治疗研究进展 被引量：7

The Immunological Mechanism and New Treatments of Alopecia Areata
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摘要 斑秃是器官特异性自身免疫性疾病,现就近年来对其毛囊免疫赦免机制的丧失、T淋巴细胞的参与等方面的研究以及免疫学治疗进展作一综述。
作者 周静 杨勤萍 黄岚
机构地区 复旦大学附属华山医院皮肤科
出处 《中国皮肤性病学杂志》 CAS 北大核心 2007年第6期368-370,共3页 The Chinese Journal of Dermatovenereology
关键词 斑秃 自身免疫性疾病 器官特异性
分类号 R758.71 [医药卫生—皮肤病学与性病学] R392.11 [医药卫生—免疫学]
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参考文献20

  • 1Barker CF,Billingham RE.Immunologically privileged sites[J].Adv Immunol,1977,25(1):1 -54.
  • 2Christoph T,Muller-Rover S,Audring H,et al.The human hair follicle immune system.cellular composition and immune privilege[J].Br J Dermatol,2000,142 (5):862 -873.
  • 3Moresi JM,Horn TD.Distribution of Langerhans cells in human hair follicle[J].J Cutan Pathol,1997,24 (10):636-640.
  • 4Gilhar A,Kam Y.Assy B,Kalish RS.Alopecia areata induced in C3H/HeJ mice by interferon-gamma:evidence for loss of immune privilege[J].J Invest Dermatol,2005,124(1):288 -289.
  • 5Gilhar A,Landau M,Assy B,et al.Melanocyte associated T-cell epitopes can function as autoantigens for transfer of Alopecia Areata to Human Scalp Explants on Prkdcscid Mice[J].J Invest Dermatol,2001,117(6):1357-1362.
  • 6Gilhar A,Ullmann Y,Berkutzki T,et al.Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice[J].J Clin Invest,1998,101 (1):62 -67.
  • 7Gilhar A,Landau M,Assy B,et al.Alopecia areata is mediated by coorperation between CD4^+ and CD8^+ T-lymphocytes:transfer to human scalp explants on Prkdcscid mice[J].Arch Dermatol,2002,138 (7):916 -922.
  • 8Gilhar A,Landau M,Assy B,et al.Transfer of alopecia areata in the human scalp graft/Prkdcscid (SCID) mouse system is characterized by a TH1 response[J].Clinical Immunol,2003,106(3):181-187.
  • 9Tang Liren,Cao Liping.Cytokines and Signal Transduction Pathways Mediated by Anthralin in Alopecia Areata Affected Dundee Experimental Balding Rats[J].J Investig Dermatol Symp Proc,2003,8 (1):87-90.
  • 10McElwee,Kevin J,Hoffmann,et al.Resistance to Alopecia Areata in C3H/ HeJ Mice Is Associated with Increased Expression of Regulatory Cytokines and a Failure to Recruit CD4^+ and CD8^+ cells[J].J Invest Dermatol,2002,119 (6):1426-1433.

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中国皮肤性病学杂志
2007年 第6期

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