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卵巢颗粒细胞瘤研究新进展 被引量:17

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摘要 颗粒细胞瘤(granulosa cell tumor,GCT),属于性索间质肿瘤,呈低度恶性,预后良好,但是有晚期复发的特点。GCT病因不明,目前研究集中于基因甲基化、染色体微卫星不稳定等方面。22号染色单体和14号染色三体的异常多见。治疗以手术为主,但由于GCT有晚期复发的特点,因此,应特别强调足够的化疗疗程及各期患者应终身随访。
出处 《国外医学(妇产科学分册)》 2007年第3期203-206,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
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  • 1Dhillon VS,Shahid M,Husain SA.CpG methylation of the FHIT,FANCF,cyclin-D2,BRCA2 and RUNX3 genes in Granulosa cell tumors (GCTs) of ovarian origin[J].Mol Cancer,2004,3:33.
  • 2Dhillon VS,Aslam M,Husain SA.The contribution of genetic and epigenetic changes in granulosa cell tumors of ovarian origin[J].Clin Cancer Res,2004,10(16):5537-5545.
  • 3Caughron SK,Bridge JA,Bewtra CB,et al.Monosomy 22 as a diagnostic aid in a case of late recurrence of adult granulosa cell tumor of the ovary[J].Cancer Genet Cytogenet,2005,156(1):83-85.
  • 4Lin YS,Eng HL,Jan YJ,et al.Molecular cytogenetics of ovarian granulosa cell tumors by comparative genomic hybridization[J].Gynecol Oncol,2005,97(1):68-73.
  • 5Dorward AM,Shultz KL,Horton LG,et al.Distal Chr 4 harbors a genetic locu (Gct1) fundamental for spontaneous ovarian granulosa cell tumorigenesis in a mouse model[J].Cancer Res,2005,65(4):1259-1264.
  • 6King DW,Steinmetz R,Wagoner HA,et al.Differential expression of GRK isoforms in nonmalignant and malignant human granulosa cells[J].Endocrine,2003,22(2):135-142.
  • 7Buters J,Ceticia QM,Schober W,et al.CYP1B1 determins susceptibility to low doses of 7,12-dimethy Ⅰ bene[α]anthracene-induced ovarian cancers in mice:correlation of CYP1B1-mediated DNA adducts with carcinogenicity[J].Carcingenesis,2003,24(2):327-334.
  • 8Jamieson S,Alexiadis M,Fuller PJ.Expression status and mutational analysis of the ras and B-raf genes in ovarian granulosa cell and epithelial tumors[J].Gynecol Oncol,2004,95(3):603-609.
  • 9Choi K,Lee HJ,Pae JC,et al.Ovarian granulosa cell tumor presenting as Meigs' syndrome with elevated CA125[J].Korean J Intern Med,2005,20(1):105-109.
  • 10Char G,Ramjit C,Fletcher H,et al.Granulosa cell tumour of the ovary with bilateral mature cystic teratomas.A case report[J].West Indian Med J,2004,53(2):135-137.

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