HIRFL浅层肿瘤重离子治疗终端束流配送系统性能的实验验证

Capability Verification of the Beam Delivery System in the Superficially-Placed Tumor Therapy Terminal at HIRFL

详细介绍了兰州重离子研究装置(HIRFL)浅层肿瘤重离子治疗终端的被动式束流配送系统,对该束流配送系统重要组成部件及其整体的性能进行了实验验证．Bragg峰展宽装置脊形过滤器及能量调节装置射程移位器测试结果显示该设备的性能指标达到设计要求．为验证该被动式束流配送系统的整体性能,进行了束流成形实验,模拟对肿瘤靶区的三维适形照射．结果表明:利用该束流配送系统可实施对肿瘤的三维适形放射治疗．HIRFL浅层肿瘤治疗装置束流配送系统性能的验证为下一步开展肿瘤重离子束治疗临床试验奠定了基础．

The passive beam delivery system in the superficially-placed tumor therapy terminal at Heavy Ion Research Facility in Lanzhou （HIRFL）, which includes two orthogonal dipole magnets as scanning system, a motor-driven energy degrader as range-shifter, series of ridge filters as range modulator and a multileaf collimator, is introduced in detail. The capacities of its important components and the whole system have been verified experimentally. The tests of the ridge filter for extending Bragg peak and the range shifter for energy adjustment show both work well. To examine the passive beam delivery system, a beam shaping experiment were carried out, simulating a three-dimensional （3D） conformal irradiation to a tumor. The encouraging experimental result confirms that 3D layer-stacking conformal irradiation can be performed by means of the passive system. The validation of the beam delivery system establishes a substantial basis for upcoming clinical trial for superficially-placed tumors with heavy ions in the therapy terminal at HIRFL.