白芍总甙胶囊治疗复发性口疮远期疗效观察

The clinical study of recurrent aphtha ulceration treated by Total Glucosides of paeony capsules

目的:探讨白芍总甙胶囊治疗复发性口疮(RAU)的远期疗效。方法:343例RAU患者分别接受白芍总甙胶囊(治疗组)、昆明山海棠片剂(对照组)治疗,观察其远期疗效,并于治疗前及停药一年后检测患者血清一氧化氮和一氧化氮合酶水平。结果:治疗组总有效率达86.71%,停药一年后血清一氧化氮及一氧化氮合酶水平显著降低(p<0.05);白芍总甙疗效优于昆明山海棠。结论:采用白芍总甙胶囊治疗RAU是一种较好的治疗方法。

Objective：To find a new effective way to treat recurrent aphtha ulceration （RAU）. Method： 343 cases were treated by Total Glucosides of paeony capsules or Kunming Shanhaitang, the late result was observed; the nitric oxide （NO） and the nitric oxide synthase （NOS） levels were examined. Result： The total effect of paeony capsules was 86.71%; The NO and NOS levels decreased significantly （P〈0.05）. Conclusion：The Total Glucosides of paeony capsules was a effective way to treat RAU.