摘要
目的 本实验利用大豆异黄酮及芦丁独特生理功能,探索大豆异黄酮复合制剂的处方设计以及工艺参数研究。方法 采用湿法制粒。结果 优选处方为大豆异黄酮40mg、牡蛎碳酸钙50mg、维生素E20mg、芦丁20mg、糖粉130mg、淀粉120mg、干淀粉10mg、硬脂酸镁2mg、滑石粉6mg。结论 所制备的片剂质量符合中国药典所规定的要求,硬度为4-7,崩解时限为10-15min。
Objective :The prescription design and the technics parameter researches were investigated,by the special physiology function of the soybean isoflavone and rutin,that the soybean isoflavone rutin compound troche. Methods :Wettished granules was prescripted. Results : The prescription was optimizated .. soybean isoflavone 40 mg ,oyster calcium carbonate 50 mg,vitamin E 20 mg,rutin 20 mg,sugar powder 130 mg,starcb 120 mg,stem starch 10 mg;stearic acid magnesium 2 mg, talcumpowder 6 mg. Conclusion: According to the standard that Chinese pharmacopoeia quantity that make to have. The hardness of troche was 4- 7,the collapse time was 10-15 minutes.
出处
《临床医药实践》
2007年第3期168-170,共3页
Proceeding of Clinical Medicine
关键词
大豆异黄酮
芦丁
钙
维生素E
soybean isoflavones
rutin
calcium
vitamin E