前列腺增生术后前列腺癌12例报告

Prostate cancer after prostatectomy for benign prostatic hyerplasia (report of 12 cases)

目的：提高对良性前列腺增生切除术后发生前列腺癌（Pea）的认识。方法：回顾性分析前列腺切除术后经病理证实的12例Pea患者资料，对其发病机制、治疗等进行探讨。结果：12例术后病理为良性前列腺增生（BPH），其中4例在术后2年内、3例在术后4～5年、2例在术后8年发生Pea，3例在术后10年以后发生。经姑息性手术及内分泌治疗，6例死于广泛转移，其余6例至今仍带瘤存活。结论：前列腺切除术后仍可能发生Pea，术后应定期随诊，可及早发现术后Pea。

Objective：To increase the knowledge of prostate cancer （Pca）which occurred after prostatectomy. Methods：Twelve cases of Pca confirmed by pathological examination after prostatectomy for benign prostatic hyperplasia （BPH）were analysed retrospectively. The mechanism and treatment of this disease were discussed with a review ofliterature. Results ：Twelve cases were all confirmed BPH by pathological examination. Four cases were found Pca af- ter prostatectomy with in 2 years,Three cases after from 4 years to 5 years ,two cases after 8 years,three cases after 10 years later. After palliative operations and endocrine therapies,six died of wide spread metastasis and six patients still survive. Conclusion：Pca can still occur after prostatectomy for BPH. The patients after prostatectomy should be followed up at regular intervals in order to make early diagnoses.