表皮生长因子受体及其单克隆抗体与口腔癌
被引量:2
Epidermal Growth Factor Receptor, its Monoconol Antibody and the Oral Cancer
摘要
表皮生长因子受体对于多种上皮源性肿瘤的发生、侵袭、转移有促进作用。通过实验已证明它的单克隆抗体对非小细胞肺癌等肿瘤细胞在体内外均有较好的抑制作用。口腔癌目前的发病趋势逐渐增高.本文对口腔癌和表皮生长因子受体及其单克隆抗体的关系进行综述。
出处
《口腔颌面外科杂志》
CAS
2007年第2期191-194,共4页
Journal of Oral and Maxillofacial Surgery
关键词
表皮生长因子受体
单克隆抗体
口腔癌
epidermal growth factor receptor
monoconal antibody
oral cancer
参考文献31
-
1Alan W.Molecules in focus EGF receptor[J].Int J Bioche Cell Bio,1999,31(8):637-643.
-
2Jill L,Reiter NJ,Maihle,et al.A 1.8 aleration transcript from the human epidermal growth receptor gene encode a truncated form the receptor[J].Nucleic Acids Re,1996,24(10):4050-4056.
-
3Giardiell F,Caputo R,Bianoco R,et al.Antitumor effect and potentation of cytotoxic drugs activity in human cancer cell by ZDl839 (Iressa),an epidermal growth factor rcceptor-selective tyrosine kinase inhibitor[J].Clin Cancer Res,2000,6(5):2053-2063.
-
4Perrotte P,Matsumoto T,Inoue K,et al.Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice[J].Clin Cancer Res,1999,5(2):257-265.
-
5Roy SH.Monoelonal antibody to target epidermal growth factor receptor positive tumors[J].Cancer,2002,94(5):1593-1611.
-
6Sclabas GM,Fujioka S,Schmidt C,et al.Restoring apoptosis in pancreatic cancer cells by targeting the nuclear factorkappaB signaling pathway with the anti-epidermal growth factor antibody IMC-C225[J].J Gastrointest Surg,2003,7(1):37-43.
-
7Janmaat ML,Giaccone G.The epidermal growth factor receptor pathway an d its inhibition as anticancer therapy[J].Durg Today(Barc),2003,39(Suppl C):61-80.
-
8Mendelsohn J.The epidermal growth factor receptor as a target for cancer therapy[J].Endocrine-Related Cancer,2001,8(1):3-9.
-
9Baselga J.The EGFR as a target for anticancer therapyfocus on cetuximab[J].European Journal of Cancer,2001,37(suppl):S16-S22.
-
10Slichenmyer WJ,Fry DW.Semin Oncol.Anticancer therapy targeting the erbB family of receptor tyrosine kinases[J].Semin Oncol,2001,28(suppl 16):67-69.
二级参考文献20
-
1曲娴,陈杰,刘彤华,高洁.人结肠癌中EGFR、EGF及TGF-α的基因表达[J].中国医学科学院学报,1994,16(4):259-263. 被引量:19
-
2[1]Van Dam PA, Lowe DE.Waston JW, et al. Multiparameter flow-cytometric quantitation of epidermal growth factor receptor and c-erbB-2 oncoprotein in normal and neoplastic tissues of the female gentital tract. Gynecol Oncol, 1991,42(3):256
-
3[2]Lopez JG, Chew ST, Thompson HW, et al. EGF cell surface receptor quatition on ocular cells by an immunocytochemical flow cytometry technique. Invest Ophtimol Vis Sci, 1992,33(6):2053
-
4[3]Melaned MR. Flow cytometry and sorting. 2nd ed. New York: John Wiley and Sons,1990.26
-
5[6]P Harari.EGFR therapies with radiation(the head and neck data).EJC,2003,1(5):S27
-
6[7]J G Eriksen,T Steiniche,J Overgard,et al,EGFR expression and histopathological differentiation influence the response to accelerated fractionation in squamous cel1 carcinomas of the head and neck(HNSCC):Analysis of 702 patients from the rardomized DAHANCA 6 and 7 trial.EJ C,2003,1(5):S204
-
7[8]M Brada,Does radiotherapy matter? EJC,2003,1(5):S28
-
8[9]G Lammering,T Hewit.J Contessa,et al.A naturally occurring type Ⅲvariant mutant EGF receptor confers strong cytoprotective response to ionizingradiation.EJC,2003,1(5):S212
-
9[10]M Bohegna,A Angelucci,L Festuccia,et al.Prostate cancer cell proliferation is strongly reduced by combination treatment with the epidermal growth factor receptor thyrosine kinase inhibitor ZD1839("iressa")and the anti-androgenbicalutamide("casodex").EJC,2003,1(5):S265
-
10[11]U Gatzemeier,J Y Douillard,M Kris,et al.Rapid and durable objective responses in patients with advanced non-small-cell lung cancer in phase Ⅱ trials(IDEAL1 and IDEM2)treated with gefitinib,EJC,2003,1(5):S20
共引文献13
-
1王海波,姜淑霞.平阳霉素联合地塞米松注射治疗舌下腺囊肿的疗效观察[J].口腔医学研究,2004,20(3):312-313. 被引量:22
-
2冯洁.介绍几种抗肿瘤的靶向新药[J].中国药师,2006,9(2):176-178. 被引量:7
-
3薛浩伟,张令达.表皮生长因子受体家族与口腔肿瘤[J].广东牙病防治,2007,15(3):131-133.
-
4张涛,蔡克瑞,王明富,田丽华,杨晶.五味子纳米醇提液对衰老小鼠脑神经细胞DNA损伤的保护作用[J].中国老年学杂志,2007,27(6):535-536. 被引量:6
-
5刘浏,蔡以理,吕燕,苏立新.人涎腺腺样囊性癌中表皮生长因子受体的表达及意义[J].口腔颌面外科杂志,2007,17(4):320-323. 被引量:5
-
6袁江兰,刘晖,康旭,邹国林.表皮生长因子受体酪氨酸激酶结构域与其抑制剂染料木素的模拟对接[J].生物工程学报,2008,24(10):1813-1817. 被引量:4
-
7石新东,赵洪洋,陈平安,黄前樟,陈绪刚,冯军.胶质瘤钴60照射后脑水肿与erb-B1蛋白表达的关系[J].肿瘤防治研究,2009,36(7):545-548. 被引量:1
-
8石新东,冯军,赵洪洋,陈平安,黄前樟,陈绪刚.地塞米松治疗放射性脑水肿与erb—B1基因转录水平的关系[J].中华神经医学杂志,2009,8(10):1024-1027. 被引量:3
-
9刘浏,胡永杰,傅锦业,吕燕,张志愿.MAB225对体外培养的ACC-2细胞增殖能力影响的研究[J].口腔颌面外科杂志,2011,21(5):314-317.
-
10张新新,王明国,邢蕾,于彦领,林夏莲,徐炜.EGFR在黏液表皮样癌中的表达[J].现代口腔医学杂志,2013,27(2):98-101. 被引量:1
同被引文献55
-
1侯亮,姜月华,詹臻.恶性肿瘤的表皮生长因子受体靶向治疗现状[J].临床肿瘤学杂志,2004,9(3):314-317. 被引量:1
-
2李丹,曾波航,于宪.转化生长因子α和表皮生长因子在恶性肿瘤的表达[J].广州医学院学报,2001,29(4):20-22. 被引量:4
-
3何海波,唐休发.E-钙粘附素/连环素复合体在口腔癌中的作用[J].国外医学(口腔医学分册),2005,32(5):359-361. 被引量:4
-
4张卫民,高岩.Wnt信号传导通路组成蛋白与口腔鳞状细胞癌的分化和增殖[J].中华口腔医学杂志,2005,40(6):491-494. 被引量:15
-
5廖小金.表皮生长因子结构和生物学效应[J].海峡药学,2006,18(5):14-17. 被引量:21
-
6Yokoyama K, Kamata N, Hayashi E, et al. Reverse correlation of E-cadberin and Snail expression in oral squamous cell carcinoma cells in vitro[J]. Oral Oncol, 2001, 37 (1):65-71.
-
7Sun L, Diamond ME, Ottaviano AJ, et al. Transforming growth faetor-beta1 promotes matrix metalloproteinase-9- mediated oral cancer invasion through snail expression [J]. Mol Cancer Res, 2008,6(1):10-20.
-
8Diamond ME, Sun L, Ottaviano AJ, et al. Differential growth factor regulation of N-cadherin expression and motility in normal and malignant oral epithelium[J]. J Cell Sci, 2008,121 (13): 2197-2207.
-
9Miyazawa J, Mitoro A, Kawashiri S, et al. Expression of mesenchyme-specific gene HMGA2 in squamouscell carcinomas of the oral cavity [J]. Cancer Res,2004,64 (6): 2024-2029.
-
10Taki M, Kamata N, Yokoyama K, et al. Down-regulation of Wnt-4 and upregulation of Wnt-5a expression by epithelial-mesenchymal transition in human squamous carcinoma cells[J]. Cancer Sci, 2003,94(7):593-607.
二级引证文献9
-
1杨巧珍,王夏夏,郭滨,孙红英.EMT在口腔鳞癌和扁平苔藓病理机制中的作用[J].口腔医学,2015,35(4):296-301.
-
2刘爱华,何安兵,童文先,王虎,田倩,彭秀兰,李晓光,徐慧琳.恶性肿瘤中HPV感染与EGFR水平的相关性[J].热带医学杂志,2016,16(5):650-653. 被引量:1
-
3翁涵,文国容,金海,庹必光.泮托拉唑对小鼠原发性肝癌中表皮生长因子(EGF)表达的影响及意义[J].遵义医学院学报,2016,39(6):584-587. 被引量:1
-
4赵国强,王佳婷,郑灵娥,张鹏,王舒仪,李江,施更生.上皮-间质转化在口腔黏膜下纤维性变中的作用[J].医学研究杂志,2017,46(3):111-115. 被引量:3
-
5谭德重,阎艾慧.VEGF与EGFR在鼻息肉发病机制中的研究进展[J].医学综述,2019,25(11):2133-2137. 被引量:5
-
6覃浩,刘俊君,李翠萍,穆婷,冯浩然,黄旋平.EMT相关调控因子Snail、Twist 1在口腔鳞状细胞癌中表达的相关性分析[J].全科口腔医学电子杂志,2019,6(23):10-14. 被引量:2
-
7刘静,范梦月,孙凯滨,孙蓉.基于分子对接柴胡桂枝干姜汤干预初期寒湿郁肺型新型冠状病毒肺炎的活性成分及功效作用机制探讨[J].中草药,2020,51(7):1704-1712. 被引量:20
-
8程佳颖,赵灵燕,白瑞霞,乔建坤,刘俊峰,岳根全,周旭颖,刘琦,高玉敏.表皮生长因子基因多态性与肾癌的相关性[J].现代肿瘤医学,2021,29(6):984-988.
-
9张丞,张慧卿,杨延龙,苏永华.中药外用治疗难愈性创面的临床研究进展[J].上海中医药大学学报,2018,32(2):100-104. 被引量:5
-
1佟倩.康莱特联合化疗对非小细胞肺癌患者生活质量改善的研究[J].现代中西医结合杂志,2007,16(11):1456-1457. 被引量:9
-
2汪祥辉,雷通海,潘娇云.乳腺癌的发病趋势及筛查[J].中国肿瘤,1996,5(6):3-6. 被引量:34
-
3陈学柏,李贤兴.女性肺癌108例分析[J].中国肿瘤临床,1992,19(2):127-129. 被引量:11
-
4高玉堂.我国常见恶性肿瘤的发病趋势[J].中国肿瘤,1996,5(1):3-6. 被引量:34
-
5李拯民,张本.我国肺癌的发病趋势[J].结核病与胸部肿瘤,1999(1):3-9. 被引量:5
-
6高玉堂.我国常见恶性肿瘤的发病趋势[J].科技导报,1996,14(1):36-38. 被引量:1
-
7廖美琳.女性肺癌[J].中国处方药,2007,6(9):52-52. 被引量:2
-
8全球癌症发病率有猛增的危险[J].首都医药,2003,10(9):27-27.
-
9佟倩.康莱特联合吉西他滨治疗老年晚期非小细胞肺癌的临床研究[J].中国医药指南,2012,10(8):31-33. 被引量:4
-
10边莉,刘翠玲,钟伟,陈亚琳,刘鹏.参麦注射液联合化疗治疗晚期非小细胞肺癌疗效观察[J].山东医药,2005,45(34):37-38. 被引量:5