摘要
目的对中药蓬莪术挥发油及其中3种主要化学成分莪术烯醇、莪术酮和异莪术烯醇进行抗肝癌和子宫内膜癌细胞活性的研究。方法用MTT法测定其抗肝癌细胞和子宫内膜癌的活性。结果和结论一定浓度的蓬莪术挥发油及其中3种主要成分莪术烯醇、莪术酮和异莪术烯醇能明显抑制肝癌细胞和子宫内膜癌细胞的生长。
OBJECTIVE To study the effects of volatileoil, curcumenol, curzerenone and isocurcumenol from Curcuma phaeocaulis Valeton on liver cancer and endometrial carcinoma cell lines. METHODS Effects of these substances on liver cancer and endometrial carcinoma cell lines were determined by MTT. RESULTS and CONCLUSION It shows that volatile oil, curcumenol, curzerenone and isocurcumenol from Curcuma phaeocaulis Valeton can inhibit the proliferation of liver cancer and endometrial carcinoma cells in different concentrations.
出处
《华西药学杂志》
CAS
CSCD
北大核心
2007年第3期312-313,共2页
West China Journal of Pharmaceutical Sciences
基金
贵阳市2006年科学技术计划项目[2006-42]
关键词
蓬莪术
莪术烯醇
莪术酮
异莪术烯醇
肝癌
子宫内膜癌
二甲基偶氮唑
Curcuma phaeocaulis Valeton
Curcumenol
Curzerenone
Isocurcumenol
Liver cancer
Endometrial carcinoma
MTT